Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (N-Term) antibody

Antigen: Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)

Synonyms: Gro1, CINC-1, CXCL1, MGSA, FSP, GRO1, GROa, NAP-3, SCYB1, MGSA-a

Epitope: N-Term

Clonality: Monoclonal (2A9)

Host: Mouse

Reactivity: Rat (Rattus)

Application: Western Blotting (WB), Neutralization (Neut)

Catalog no.: ABIN180030

Additional Information

Alternative name: GRO/CINC-1 N-terminal

Immunogen: Synthetic peptide to N-terminal of Rat GRO/CINC-1

Isotype: IgG1

Clone: 2A9

Description: Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1stimulated rat kidney epithelioid cells (NRK-52E). Amino acid sequence that encodes for rat CINC-1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC-1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC-2, CINC-2, CINC-3/MIP-2) have been identified. The protein sequence of CINC-1 is 63 - 67% identical to that of CINC-2, CINC-2, CINC-3/MIP-2. In addition, GRO, GRO and GRO is sharing 68%, 71% and 69%, identity with CINC-1. This has been suggested that CINCs are the rat counterpart of human GROs.

Specificity: Does not react with Rat GRO/CINC-1 C-terminal, Rat GRO/CINC-2alpha, Rat GRO/CINC-2beta, Rat GRO/CINC-3, Mouse MIP-2, Human GRO alpha and Human IL-8.

Application Details

Application Notes: This antibody can be used for western blotting in concentration of 2-5 ug/ml. This antibody also can be used for neutralization assay in concentration at 1-00 ug/ml.

Purification: Protein A

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Storage: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Restrictions: For Research Use only