Endothelin 1 (EDN1) antibody
| Antigen |
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| Synonyms |
ET1, HDLCQ7, EDN1, EDN, ET-1, Edn1, et1, et-1, preproET, Et1, fb14d01, wu:fb14d01, PPET1, PPET-1 |
| Clonality |
Monoclonal (9H) |
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Host
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Application
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Enzyme Immunoassay (EIA) (17), Radioimmunoassay (RIA) (17), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Western Blotting (WB) (8), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), ELISA (4), ELISA (Detection) (2), Immunoradiometric Assay (IRMA) (2), ELISA (Capture) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
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| Catalog no. |
ABIN180033 |
| Quantity |
500 µg |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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Endothelin-1
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Immunogen
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Synthetic peptide of a part of ET-1 (Common parts with Human, Bovine, Canine, Mouse, Porcine, and Rat)
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Isotype
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IgG2b (Matching secondary antibodies)
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Clone
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9H
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Description
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Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the endothelin-converting enzyme. These peptides possess many biological activities, such as vasoconstriction and mitogenesis, and are involved in numerous physiological and pathophysiological processes in humans. Elevated plasma levels of endothelin have been associated with heart failure, and increased immunoreactivity for endothelin is observed in transplant coronary artery disease. Endothelin-1 (ET-1) is known as the most potent vasoconstrictor substance.
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Specificity
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Endothelin-1 100.0 % Endothelin-2 100.0 % Endothelin-3 100.0 % Big Endothelin-1 100.0 % Big Endothelin-2 100.0 % Big Endothelin-3 100.0 % VIC 100.0 % No crossreactivities with Endothelin(15-21)
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Application Notes
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ELISA
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Purification
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Protein A
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Buffer
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Lyophilized product from 1% BSA in PBS . Reconstitution: 1 ml distilled water will be added to the product
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Storage
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Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
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Research Area
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Hormones
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Restrictions
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For Research Use only
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Alternatives for antigen "Endothelin 1 (EDN1)", type "Antibodies"
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Hosts
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Rabbit (17), Mouse (15), Sheep (1)
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Reactivities
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Human (27), Pig (Porcine) (3), Cow (Bovine) (2), Rat (Rattus) (1), Sheep (Ovine) (1)
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Applications
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Enzyme Immunoassay (EIA) (17), Radioimmunoassay (RIA) (17), Immunohistochemistry (IHC) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (8), Western Blotting (WB) (8), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), ELISA (4), ELISA (Detection) (2), Immunoradiometric Assay (IRMA) (2), ELISA (Capture) (1), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Biotin (2)
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Epitopes
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C-Term (2), AA 22-38 (1)
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Alternatives 
