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Antibodies
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anti-S-100 Protein (alpha chain) antibody
S-100 Protein (alpha chain) antibody
| Antigen |
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| Clonality |
Monoclonal (2A10) |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN180036 |
| Quantity |
0,5 ml (Variants) |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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S-100 Protein
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Immunogen
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Bovine Brain S-100 Protein
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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2A10
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Description
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S100 proteins (16 members) show a very divergent pattern of cell- and tissue-specific expression, of subcellular localizations and relocations, of post-translational modifications, and of affinities for Ca2+, Zn2+, and Cu2+, consistent with their pleiotropic intra- and extracellular functions. Up to 40 target proteins are reported to interact with S100 proteins and for S100A1 alone 15 target proteins are presently known. Therefore it is not surprising that many functional roles have been proposed and that several human disorders such as cancer, neurodegenerative diseases, cardiomyopathies, inflammations, diabetes, and allergies are associated with an altered expression of S100 proteins.
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Specificity
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React to chain of Bovine and Human S-100 protein
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Application Notes
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This antibody can be stained in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is X 2-00, however, the dilution rate should be optimized by each laboratories.
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 0.5 ml distilled water will be added to the product
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Storage
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Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
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Restrictions
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For Research Use only
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Alternatives for antigen "S-100 Protein (alpha chain)", type "Antibodies"
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Hosts
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Mouse (37), Rabbit (34)
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Reactivities
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Human (34), Cow (Bovine) (26), Rat (Rattus) (4), Cat (Feline) (2), Mouse (Murine) (2), Pig (Porcine) (2), Rabbit (2)
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Applications
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (32), Western Blotting (WB) (27), ELISA (25), Immunohistochemistry (IHC) (13), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), Enzyme Immunoassay (EIA) (4), Radioimmunoassay (RIA) (4), Immunocytochemistry (ICC) (2), Immunofluorescence (IF) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Biotin (3)
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Alternatives 
