MDMX antibody
| Antigen |
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| Clonality |
Monoclonal (77A1) |
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Host
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Reactivity
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Human (17), Mouse (Murine) (17), Rat (Rattus) (16), Horse (Equine) (6), Cow (Bovine) (4), Dog (Canine) (4), Pig (Porcine) (4), Rabbit (4), Chicken (3), Sheep (Ovine) (2), Guinea Pig (1)
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Application
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| Catalog no. |
ABIN180048 |
| Quantity |
100 µg |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Immunogen
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Human MDMX Recombinant protein
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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77A1
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Description
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The p53 tumor suppressor protein is stabilized in response to cellular stress, resulting in activation of genes responsible for either cell cycle arrest or apoptosis. The cellular pathway for releasing normal cells from p53- dependent cell cycle arrest involves the MDM2 protein. Recently, a p53- binding protein with homology to MDM2 was identified and called MDMX. Like MDM2, MDMX is able to bind p53 and inhibit p53 transactivation. It is proposed that the MDMX protein may function to maintain a nuclear pool of p53 protein in undamaged cells.
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Application Notes
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This antibody can be used for western blotting in concentration of about 1 - 5 ug/ml. Not tested in application for immunohistochemical staining
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Purification
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Protein A
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product
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Storage
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Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
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Restrictions
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For Research Use only
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Alternatives for antigen "MDMX", type "Antibodies"
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Hosts
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Rabbit (18), Mouse (1)
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Reactivities
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Human (17), Mouse (Murine) (17), Rat (Rattus) (16), Horse (Equine) (6), Cow (Bovine) (4), Dog (Canine) (4), Pig (Porcine) (4), Rabbit (4), Chicken (3), Sheep (Ovine) (2), Guinea Pig (1)
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Applications
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Flow Cytometry (FACS) (16), Immunofluorescence (IF) (15), Western Blotting (WB) (2), ELISA (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Alternatives 
