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Endothelin Receptor Type B (EDNRB) (8Z11) antibody
| Antigen | Endothelin Receptor Type B (EDNRB) |
| Synonyms | ETB, ETBR, ETRB, HSCR, ABCDS, HSCR2, s, ETb, ET-B, ET>B<, ETR-b, Sox10m1, AU022549, Etb, Ednra, MGC142327, EDNRB, etb, etrb, hscr, abcds, hscr2, MGC145633, ednrb, MGC147408 |
| Epitope |
 Alternatives 8Z11 |
| Clonality | Monoclonal (8Z11) |
| Host |
Alternatives Mouse |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP)
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| Catalog no. | ABIN180056 |
| Quantity | 100 µg |
| Price | 517.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 10 to 15 Business Days |
Additional Information
| Alternative name | ET-BR (Endothelin-B Receptor) (8Z11) |
| Immunogen | ET-1bound recombinant human 6hN-ETBR produced in insect sf-9 cells |
| Isotype | IgG2a (Matching secondary antibodies) |
| Clone | 8Z11 |
| Description | Two kinds of receptors for Endothelin have been found, namely Endothelin-A (ET-A) receptor and Endothelin-B (ET-B) receptor. ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in liver, lung, placenta, kidney, heart and brain. Cellular localization of ET-receptors in these organs or tissues, however, has not been elucidated, although stromal cells, but not epithelial cells of the breast, express ET-1 receptor in vitro. |
| Specificity | Confirmed by western blotting |
Application Details
| Application Notes | This antibody can be stained in formalin fixed paraffin embedded tissues with micro wave pretreatment (10min, 1-0mM Citrate buffer, pH 5.0) by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is about 5 ug/ml, however, the dilution rate should be optimized by each laboratories. *1 rinsing by running water after formic acid treatment for 5 minutes following de-paraffin. This antibody can be used for western blotting in concentration of 2 - 5 ug /ml. |
| Purification | Recombinant human ET-BR |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product |
| Storage | Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20 |
| Restrictions | For Research Use only |
Alternatives
Alternatives for antigen "Endothelin Receptor Type B (EDNRB)", type "Antibodies"
| Hosts | Rabbit (12), Goat (1), Mouse (1) |
| Reactivities | Human (12), Rat (Rattus) (3), Mouse (Murine) (2) |
| Applications | Western Blotting (WB) (14), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), ELISA (2), Immunoprecipitation (IP) (2), Enzyme Immunoassay (EIA) (1), Immunofluorescence (IF) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1) |
| Epitopes | C-Term (5), B27 (1), N-Term (1) |
