V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT) antibody

Antigen: V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog (KIT)

Synonyms: PBT, SCFR, C-Kit, CD117, W, Bs, Fdc, Ssm, SCO1, SCO5, SOW3, c-KIT, Tr-kit, Gsfsco1, Gsfsco5, Gsfsow3, c-kit, kit-A, XKrk1, KIT, MGF, LOC100221238, C-KIT

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC)

Catalog no.: ABIN180114

Additional Information

Alternative name: c-kit (k963)

Immunogen: Synthetic peptide for C-terminal of human c-Kit Purification: Affinity Purified with synthetic peptide, then FITC was conjugated.

Isotype: IgG  (Matching secondary antibodies)

Description: The proto-oncogene c-kit encodes a transmembrane tyrosine kinase receptor, and its ligand for c-kit receptor has been identified as the stem cell factor (SCF). Recent experimental studies have shown that c-kit plays a key role in the development of a component of the pacemaker system that is required for generation of autonomic gut motility. These studies further suggest that interaction of the c-kit and SCF is essential for development of enteric nervous system.

Specificity: Human c-Kit (M.W.145kDa) specific

Application Details

Application Notes: This antibody can be stained in formalin fixed paraffin embedded tissues with immuno-fluorescence method. The optimal dilution is 1-10 ug/ml, however, the dilution rate should be optimized by each laboratories.

Purification: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Storage: Lyophilized product, 5 years at 2 ­ 8 : Solution, 2 years at ­20

Research Area: Proliferation Markers

Restrictions: For Research Use only