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Antibodies
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anti-Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha...
Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1) (N-Term) antibody
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| Synonyms |
Gro1, CINC-1, CXCL1, MGSA, FSP, GRO1, GROa, NAP-3, SCYB1, MGSA-a |
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Epitope
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB), Neutralization (Neut)
Western Blotting (WB) (48), ELISA (20), Enzyme Immunoassay (EIA) (17), Functional Studies (Func) (8), Neutralization (Neut) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunohistochemistry (IHC) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1)
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| Catalog no. |
ABIN180136 |
| Quantity |
100 µg |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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GRO/CINC-1 N-terminal
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Immunogen
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Synthetic peptide for N-Terminal of rat GRO/CINC-1 conjugating bovine thyroglobulin Purification: Affinity Purified with synthetic peptide
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Isotype
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IgG
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Description
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Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1 Àstimulated rat kidney epithelioid cells (NRK-52E). Amino acid sequence that encodes for rat CINC-1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC-1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC-2¿ , CINC-2À , CINC-3/MIP-2) have been identified. The protein sequence of CINC-1 is 63 - 67% identical to that of CINC-2¿ , CINC-2À , CINC-3/MIP-2. In addition, GRO¿ , GROÀ and GROÁ is sharing 68%, 71% and 69%, identity with CINC-1. This has been suggested that CINCs are the rat counterpart of human GROs.
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Specificity
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Rat GRO/CINC-1 (100%), Rat GROÀ /MIP2 (<0.1%), Human IL-8 (<0.1%), Human GRO¿ (1.56%) Chemotactic: Inhibit migration of neutrophil (up to 6 nM) at 10Ê ug/ml Activity
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Application Notes
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This antibody can be stained both in frozen sections and in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is 2 - 5 ug/ml, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of 2 - 5 ug/ml.
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Purification
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Antigen peptide
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product
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Storage
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Lyophilized product, 5 years at 2 8 C : Solution, 2 years at 20 C
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Restrictions
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For Research Use only
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Alternatives for antigen "Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, Alpha) (CXCL1)", type "Antibodies"
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Hosts
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Rabbit (43), Mouse (7), Goat (1)
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Reactivities
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Human (20), Rat (Rattus) (18), Mouse (Murine) (12)
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Applications
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Western Blotting (WB) (48), ELISA (20), Enzyme Immunoassay (EIA) (17), Functional Studies (Func) (8), Neutralization (Neut) (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunoprecipitation (IP) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunohistochemistry (IHC) (2), ELISA (Detection) (1), Immunocytochemistry (ICC) (1)
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Conjugates
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Biotin (12)
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Epitopes
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C-Term (2), N-Term (1)
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