GRO/CINC-2alpha, -2beta (N-Term) antibody

Antigen: GRO/CINC-2alpha, -2beta

Epitope: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN180139

Additional Information

Alternative name: GRO/CINC-2alpha, -2beta N-terminal

Immunogen: Synthetic peptide for N-Terminal common sequences of rat GRO/CINC-2¿ and rat GRO/CINC-2À conjugating bovine thyroglobulin Purification: Affinity Purified with synthetic peptide

Isotype: IgG  (Matching secondary antibodies)

Description: Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1 Àstimulated rat kidney epithelioid cells (NRK-52E). Amino acid sequence that encodes for rat CINC-1 was identified in 1989 by Watanabe's group at Toyama Medical and Pharmaceutical University. CINC-1 is a member of the alpha (CXC) subfamily of chemokines. Three additional rat CXC chemokines (CINC-2¿ , CINC-2À , CINC-3/MIP-2) have been identified. The protein sequence of CINC-1 is 63 - 67% identical to that of CINC-2¿ , CINC-2À , CINC-3/MIP-2. In addition, GRO¿ , GROÀ and GROÁ is sharing 68%, 71% and 69%, identity with CINC-1. This has been suggested that CINCs are the rat counterpart of human GROs.

Specificity: React with Rat GRO/CINC-2 ¿and ­2 À. No crossreactivities with Rat GRO/CINC-1 and Rat GRO/CINC-3.

Application Details

Application Notes: This antibody can be used for western blotting in concentration of 2 - 5 ug/ml.

Purification: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product

Storage: Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C

Restrictions: For Research Use only