COX-2 antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN180169 |
| Quantity |
100 µg (Variants) |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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COX-2 (C580)
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Immunogen
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Synthetic peptide for a part of Rat COX-2 Purification: Affinity Purified with synthetic peptide
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Cyclooxygenase (COX) is a membrane bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2 to PHG2. These reactions are the first steps in the formation of a variety of prostanoids. COX has been shown to be expressed in at least two different isoforms, a constitutively expressed form, COX-1, and an inducible form, COX-2. COX-1 is thought to regulate a number of housekeeping functions, such as vascular hemostasis, renal blood flow, and maintenance of glomerular function. Inflammation mediators such as growth factors, cytokines and endotoxin induce COX-2 expression in a number of cellular systems.
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Specificity
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Rat COX-2 specific. No crossreactivities with Human COX-2 and Rat COX-1. Reactivity:React with Rat Macrophage stimulated with LPS.
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Application Notes
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This antibody can be used for western blotting in concentration of 2-5 ug/ml.
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Purification
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Antigen peptide
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05%NaN3 . Reconstitution: 1 ml distilled water will be added to the product
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Storage
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Lyophilized product, 5 years at 2 8 : Solution, 2 years at 20
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Restrictions
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For Research Use only
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Alternatives for antigen "COX-2", type "Antibodies"
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Hosts
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Rabbit (15), Mouse (2)
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Reactivities
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Human (13), Rat (Rattus) (5), Mouse (Murine) (1), Sheep (Ovine) (1)
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Applications
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Western Blotting (WB) (14), Immunohistochemistry (IHC) (11), Immunofluorescence (IF) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), ELISA (1), Immunocytochemistry (ICC) (1)
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Alternatives 
