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Antibodies
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anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody
TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody
| Antigen |
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| Synonyms |
EPA, EPO, HCI, CLGI, TIMP, FLJ90373, TIMP1, TIMP-1, DKFZp468A0912 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (67), Rat (Rattus) (6), Cow (Bovine) (4), Mouse (Murine) (3), Horse (Equine) (2), Rabbit (2), Sheep (Ovine) (2), Ferret (1), Hamster (1), Macaque (1), Monkey (1)
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Application
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Western Blotting (WB) (69), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), ELISA (29), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (IHC) (6), ELISA (Detection) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Flow Cytometry (FACS) (1), Functional Studies (Func) (1), Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) (1)
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| Catalog no. |
ABIN180201 |
| Quantity |
100 µg |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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TIMP-1 (T172)
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Immunogen
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The part of Synthetic peptide of TIMP-1 protein (177-188) Purification: Purified with antigen peptide
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Tissue inhibitor of Metalloprotinase (TIMP-1) is endogenous-specific inhibitor produced simultaneously with matrix metalloproteinase (MMP). TIMP-1 inhibits both active MMP to control degeneration of extracellular matrix (ECM) and conversion of intermediate form into active form. In addition, TIMP-1 forms complex with not only active MMP but also potential MMP. Especially, TIMP-1 binds to potential MMP-9 by affinity of C-terminal domain to one another. The degeneration of extracellular matrix is essential step in invation and metastasis of tumor cell. It is considered that tumor cell collects protease on the surface of cell and degenerates ECM in invading tissue.
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Specificity
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Confirmed by Recombinant TIMP-1
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Application Notes
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This antibody can be used for western blotting in concentration of 1~5 ug/ml.
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Purification
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Antigen peptide
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product (In storing, please add NaN3 to the products after reconstitution)
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Storage
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Lyophilized product, 5 years at 2 8 C : Solution, 2 years at 20 C
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Restrictions
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For Research Use only
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Alternatives for antigen "TIMP Metallopeptidase Inhibitor 1 (TIMP1)", type "Antibodies"
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Hosts
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Mouse (48), Rabbit (28), Rat (1)
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Reactivities
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Human (67), Rat (Rattus) (6), Cow (Bovine) (4), Mouse (Murine) (3), Horse (Equine) (2), Rabbit (2), Sheep (Ovine) (2), Ferret (1), Hamster (1), Macaque (1), Monkey (1)
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Applications
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Western Blotting (WB) (69), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (34), ELISA (29), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunohistochemistry (IHC) (6), ELISA (Detection) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Flow Cytometry (FACS) (1), Functional Studies (Func) (1), Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) (1)
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Conjugates
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Biotin (5)
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Epitopes
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N-Term (2), Ab-2 (1), C-Term (1)
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Alternatives 
