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MBD2 (Methylated DNA Binding Domain 2) antibody
| Antigen | MBD2 (Methylated DNA Binding Domain 2) |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN180217 |
| Quantity | 100 µg |
| Price | 517.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 10 to 15 Business Days |
Additional Information
| Immunogen | Synthetic peptide of part of C terminal of human MBD2 (TEEMDIEMDSGDEA) Purification: Purified with antigen peptide |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG-binding domain (MBD) can bind to single methylated CpGs and ,ost of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: BD1, MBD2, MBD3, MBD4 and MECP2. |
| Specificity | No cross-reactivities with MBD3 (by western blotting) |
Application Details
| Application Notes | This antibody can be used for western blotting at about 2 ug/ml. |
| Purification | Antigen peptide |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 ml distilled water will be added to the product, then its concentration comes to 100 ug/ml |
| Storage | Lyophilized product, 5 years at 2 8 C : Solution, 2 years at 20 C |
| Restrictions | For Research Use only |
