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Claudin 6 (CLDN6) antibody

Antigen

Claudin 6 (CLDN6)
Synonyms AL024037, cldn6, MGC81720, CLDN6
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Mouse (Murine)
Application
Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Catalog no. ABIN180218
Quantity 100 µg
Price 517.00 $   Plus shipping costs $35.00
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anti-Claudin 6 (CLDN6) antibody

anti-Claudin 6 (CLDN6) antibody (2)

anti-Claudin 6 (CLDN6) antibody (3)

Additional Information
Application Details Images Alternatives Secondary Antibodies back to top

Alternative name Claudin-6 (C)
Immunogen Synthetic peptide of part of C terminal of Mouse Claudin-6 (SRGPSEYPTKNYV) Purification: Purified with antigen peptide
Isotype IgG  (Matching secondary antibodies)
Description The tight junction is identified as a belt-like region in which two lipid-apposing membranes lie close together (tight junction strands). Tight junction strands of the adjacent cells form tightly connected pairs. The proteins involved in the formation of tight junctions are divided into two categories: 1) integral membrane proteins, such as occludin, claudin and junctional adhesion molecule, JAM and 2) peripheral membrane proteins (cytoplasmic plaque proteins), MAGUK (membrane-associated guanylate kinase) homologue proteins, such as ZO-1, 2, 3, cingulin, symplekin, 19B1, and AF-6. In human, the claudin superfamily consists of at least 18 members, which are involved on paracellular transport as structural and functional components of tight junction. Claudins are directly associated with ZO-1, 2 and 3 and indirectly with AF-6 and cingulin.
Specificity Claudin-6 specific. No crossreactivities with Claudin-1, -2, -3, -4, -5, -7, -8, -12, and -15 (This confirmed by western blotting using each transfectants)

Application Details
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Application Notes This antibody can be stained in frozen tissues by several Immunohistochemical techniques such as immunofluoroscent method. The optimal dilution is about 5 ug/mL, however, the dilution rate should be optimized by each laboratories.:This antibody can be used for western blotting in concentration of about 1ug/mL.
Purification Antigen peptide
Buffer Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 . Reconstitution: 1.0 mL distilled water will be added to the product, then its concentration comes to 100 ug/mL
Storage Lyophilized product, 5 years at 2 ­ 8 C : Solution, 2 years at ­20 C
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies back to top

Alternatives for antigen "Claudin 6 (CLDN6)", type "Antibodies"
Hosts Rabbit (25)
Reactivities Human (24), Mouse (Murine) (22), Rat (Rattus) (18), Cow (Bovine) (1), Dog (Canine) (1), Horse (Equine) (1)
Applications Immunofluorescence (IF) (20), Flow Cytometry (FACS) (18), Western Blotting (WB) (8), ELISA (5), Immunohistochemistry (IHC) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoprecipitation (IP) (2), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pTyr219 (1)