Septin 7 (SEPT7) (C-Term) antibody

Antigen: Septin 7 (SEPT7)

Synonyms: CDC3, CDC10, SEPT7A, Nbla02942, Cdc10, KIAA4020, mKIAA4020, E430034N22, sept7, MGC56383, zgc:56383, cdc10, MGC84100, DKFZp459M152, DKFZp459P029, DKFZp459B0314, DKFZp459O0215

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Catalog no.: ABIN180242

Additional Information

Alternative name: Septin 7 (C)

Immunogen: The C terminal part of synthetic peptide of Human Septin 7 NSSRTLEKNKKKGKIF Purification: Purified with antigen peptide

Isotype: IgG  (Matching secondary antibodies)

Description: A cytoskeletal or scaffold protein family named septin has been shown to be involved in diverse phenomena in the living body, including cell division. The term septin is derived from septation, which means division. The protein was discovered as a GTP-bound protein (a polymer) indispensable for the division of yeast cells. Several to dozens of septin subunits are linked together to form filaments tens of nanometers in length. Multiple such filaments combine to form structures assuming the shapes of ribbons, rings or spirals, measuring on the order of submicrons in size. In multicellular organisms, septin is known to be involved in cell division as well as in diverse cell functions after differentiation, although the exact nature of its actions remain to be determined. Septin 7 (hcdc 10), one of the most important subunits of the mammalian septin family, is known to be expressed in all cells. Abnormal levels or locations of septin expression have been reported in humans with cancer, degenerative neurological diseases (e.g., Alzheimer's disease), male sterility, etc.

Specificity: Crossreactivities with mouse and rat.

Application Details

Application Notes: This antibody can be stained in formalin fixed paraffin embedded tissues by several Immunohistochemical techniques such as Avidin Biotin Complex (ABC) Method. The optimal dilution is about 1-5 ug /mL, however, the dilution rate should be optimized by each laboratories. This antibody can be used for western blotting in concentration of about 0.1-1 ug /mL.

Purification: Antigen peptide

Buffer: Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 Reconstitution: 1.0 mL distilled water will be added to the product (The conc. comes up 100 ug /mL)

Storage: Lyophilized product, 5 years at 2 ­ 8

Restrictions: For Research Use only

Images

anti-Septin 7 (SEPT7) (C-Term) antibody