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Rheb (R165) antibody
| Antigen | Rheb (R165) |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human |
| Application |
Western Blotting (WB), Immunoprecipitation (IP)
|
| Catalog no. | ABIN180250 |
| Quantity | 100 µg |
| Price | 517.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 10 to 15 Business Days |
Additional Information
| Immunogen | Synthetic peptide of the C-terminal part of Human Rheb (LEAEKMDGAASQGKSS) Purification: Purified with antigen peptide |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Rheb (ras homolog enriched in brain) is a 20 kDa protein identified as a Ras homolog expressed in the rat hippocampus, but it widely exists in a variety of cells. It is also reported that GTP-binding form is predominant in Rheb, unlike other low molecular weight GTP-binding proteins. While it is clear that GAP of Rheb is TSC2 which is the gene product of TS (tuberous sclerosis), TCTP (translationally controlled tumor protein) is reported to be expected as a GEF of Rheb. It is known that over-expression of Rheb can rescue the function of mTOR from inactivation by amino-acid starvation, and it is clear that Rheb acts as an activator of mTOR signaling cascade. |
Application Details
| Application Notes | This antibody can be used for western blotting in concentration of 0.5-5 ug /mL. This antibody can be used for immunoprecipitation in concentration of 1-5 ug /mL. |
| Purification | Antigen Peptide |
| Buffer | Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 Reconstitution: 1.0 mL deionized water will be added to the product (the conc. comes up 100 ug /mL) |
| Storage | Lyophilized product, 5 years at 2 - 8 °C |
| Restrictions | For Research Use only |
