Drebrin 1 (DBN1) antibody
| Antigen |
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| Synonyms |
D0S117E, DKFZp434D064, DBN1, MGC138067, LOC733967 |
| Clonality |
Polyclonal |
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Host
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Application
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 Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Immunofluorescence (IF) (35), Flow Cytometry (FACS) (29), Western Blotting (WB) (14), Immunoprecipitation (IP) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), ELISA (4), Immunohistochemistry (IHC) (3), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1)
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| Catalog no. |
ABIN180253 |
| Quantity |
50 µg |
| Price |
517.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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Drebrin-A (DAS2)
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Immunogen
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Synthetic peptide of the part of Drebrin A (FIKASDSGPSSS) Purification: Purified with antigen peptide
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Drebrin (developmentally regulated brain protein), isolated and identified from chicken brain as a protein associated with brain development, is conserved over species, and there are two types of isoforms, drebrin A and drebrin E in mammalian such as rat and human. Drebrin has actin filament-binding activity and has drawn attention as a protein generally involved in biological phenomena related to intracellular actin cytoskeletal system including cell migration. Drebrin A is present specifically at neuron dendritic spines in adult brain and is considered to be related in its morphogenesis, synaptic transmitter function and plasticity. Drebrin A is reported to decrease in Alzheimer's disease, Down syndrome and aged brain, and it is suggested that drebrin A is related to decline of cognitive function. This antibody specifically reacts with drebrin A among isoforms of drebrin.
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Specificity
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Reacts with rat and mouse Drebrin A.
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Application Notes
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This antibody can be used for immunohistochemistry with frozen sections in concentration of 0.325 - 0.65 ug /mL.: This antibody can be used for immunocytochemistry in concentration of 0.325 - 0.65 ug /mL.
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Purification
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Antigen peptide
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Buffer
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Lyophilized product from 1% BSA in PBS containing 0.05% NaN3 Reconstitution: 1.0 mL deionized water will be added to the product (The conc. comes up 50 ug /mL)
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Storage
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Lyophilized product, 5 years at 2 - 8 °C
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Restrictions
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For Research Use only
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Alternatives for antigen "Drebrin 1 (DBN1)", type "Antibodies"
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Hosts
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Rabbit (33), Mouse (6), Guinea Pig (4)
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Reactivities
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Human (38), Mouse (Murine) (24), Rat (Rattus) (23), Cow (Bovine) (22), Dog (Canine) (20), Pig (Porcine) (17), Rabbit (17), Chicken (15), Horse (Equine) (15)
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Applications
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Immunofluorescence (IF) (35), Flow Cytometry (FACS) (29), Western Blotting (WB) (14), Immunoprecipitation (IP) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), ELISA (4), Immunohistochemistry (IHC) (3), Immunoelectron Microscopy (IEM) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Enzyme Immunoassay (EIA) (1)
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Conjugates
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Biotin (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy7 (2), RBITC (2), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), PE,Cy5.5 (1)
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Epitopes
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C-Term (2)
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