You are viewing an incomplete version of our website. Please click to reload the website as full version.

TNFRSF14 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 14)

Details for Product anti-TNFRSF14 Antibody No. ABIN180391, Supplier: Log in to see
Antigen
  • ATAR
  • Atar
  • CD270
  • HVEA
  • HveA
  • HVEM
  • Hvem
  • LIGHTR
  • Tnfrs14
  • TR2
Reactivity
Human
138
22
1
Host
Mouse
74
52
14
8
4
Clonality (Clone)
Monoclonal ()
Conjugate
This TNFRSF14 antibody is un-conjugated
14
12
7
6
4
3
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF)
103
58
51
30
20
11
10
7
6
2
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Immunogen Recombinant human TR2 proteinRemarks: Mol. Wt. of Antigen: 32 kDa
Clone 122
Isotype IgG1
Specificity This antibody detects TNF Receptor like 2.
Cellular Localization: Secreted protein.
Characteristics Synonyms: HVEA, Herpesvirus entry mediator A, TR2, Tumor necrosis factor receptor superfamilymember 14, Tumor necrosis factor receptor-like 2
Purification Protein G chromatography
Alternative Name TNFRSF14 / HVEM (TNFRSF14 Antibody Abstract)
Background TNF receptor like-2 (TR2) (also known as herpesvirus entry mediator (HVEM)) is expressed in multiple human tissues and cell lines and shows a constitutive and relatively high expression in peripheral T and B lymphocytes, and monocytes. It is a member of TNF receptor family. TR2/HVEM is a receptor for herpes virus. It also acts as a receptor for LIGHT (also known as HVEM ligand), a member of TNF family. TR2 protein inhibits a mixed lymphocyte reaction-mediated proliferation suggesting that the receptor and/or its ligand play a role in T cell stimulation.Synonyms: HVEA, Herpesvirus entry mediator A, TR2, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 2
Gene ID 8764
UniProt Q92956
Application Notes Flow Cytometry. Function Blocking (Order Ab without Azide). Immunofluorescence. Recommended positive control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.2 mg/mL
Buffer 10 mM PBS, pH 7.4, with 0.2 % BSA and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C for one month or in aliquots at -20 °C for longer.
Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Zhai, Guo, Hsu, Yu, Ni, Kwon, Jiang, Lu, Tan, Ugustus, Carter, Rojas, Zhu, Lincoln, Endress, Xing, Wang, Oh, Gentz, Ruben, Lippman, Hsieh, Yang: "LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transfer." in: The Journal of clinical investigation, Vol. 102, Issue 6, pp. 1142-51, 1998

Mauri, Ebner, Montgomery, Kochel, Cheung, Yu, Ruben, Murphy, Eisenberg, Cohen, Spear, Ware: "LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator." in: Immunity, Vol. 8, Issue 1, pp. 21-30, 1998

Kwon, Tan, Ni, Oh, Lee, Kim, Kim, Wang, Gentz, Yu, Harrop, Lyn, Silverman, Porter, Truneh, Young: "A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation." in: The Journal of biological chemistry, Vol. 272, Issue 22, pp. 14272-6, 1997

Montgomery, Warner, Lum, Spear: "Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family." in: Cell, Vol. 87, Issue 3, pp. 427-36, 1996

Did you look for something else?