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Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibody

Details for Product No. ABIN180669
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Antigen
Reactivity
Human
(221), (69), (65), (25), (21), (14), (4), (4), (2), (2), (2), (1), (1), (1), (1)
Host
Mouse
(124), (84), (14), (12), (7), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (4), (3), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(200), (88), (66), (64), (31), (20), (17), (10), (4), (3), (2), (1)
Pubmed 2 references available
Quantity 0.5 mL
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Catalog No. ABIN180669
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Immunogen Recombinant protein corresponding to full length human protein gene product 9. 5molecule. Remarks: Mol. Wt. of Antigen: 25-27 kDa
Clone 10A1
Isotype IgG2b
Characteristics Synonyms: UCH-L1, PGP 9.5, Ubiquitin thioesterase L1, Neuron cytoplasmic protein 9.5, Ubiquitincarboxyl-terminal hydrolase isozyme L1
Purification Supernatant
Alternative Name UCHL1 / PGP9.5
Background Protein gene product 9. 5 is a ubiquitin C-termianl hydroxylase found in neurons and nervefibres of central and peripheral nervous system, many neuroendocrinal cells, segments ofrenal tubules, spermatogonia, leydig cells of testis, and ova. It is present in cellularinclusions and can be a useful as a neuronal marker and in the studies ofneurodegenerative disorders.
UniProt P09936
Research Area Tags/Labels, Cell/Tissue Markers
Application Notes Immunohistochemistry on Paraffin Sections: 1/10 for 60 min at RT, staining ofFormalin-Fixed tissues REQUIRES boiling tissue sections in 10 mM citrate buffer, pH 6.0, for10-20 min followed by cooling at RT for 20 min. Positive Control: Small intestine. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibody anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) antibody
Background publications Wilkinson, Lee, Deshpande et al.: "The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase." in: Science (New York, N.Y.), Vol. 246, Issue 4930, pp. 670-3, 1989 (PubMed).

Wilson, Barber, Hamid et al.: "The immunolocalization of protein gene product 9.5 using rabbit polyclonal and mouse monoclonal antibodies." in: British journal of experimental pathology, Vol. 69, Issue 1, pp. 91-104, 1988 (PubMed).

Validation Images
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