Enkephalin antibody

Catalog No. ABIN180908

Product Details anti-Enkephalin Antibody

Target: Enkephalin (PENK) (Proenkephalin (PENK))

Reactivity: Mammalian

Host: Mouse

Clonality: Monoclonal

Conjugate: This Enkephalin antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to MET-Enkephalin. Cross reactivities with other enkephalins to be determined.

Purification: Protein A chromatography

Immunogen: Native.

Clone: 1194-334

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.1 mg/mL

Buffer: PBS, pH 7.2 containing 10 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Enkephalin

Target: Enkephalin (PENK) (Proenkephalin (PENK))

Alternative Name: Proenkephalin-A (PENK) (PENK Products)

Synonyms: AI326464 antibody, ENK antibody, PPA antibody, Penk1 antibody, PENK antibody, penk antibody, Enk antibody, Penk-rs antibody, Penk2 antibody, penkl antibody, zgc:73353 antibody, Penk antibody, proenkephalin antibody, preproenkephalin antibody, proenkephalin b antibody, proenkephalin L homeolog antibody, proenkephalin a antibody, PENK antibody, Penk antibody, penk antibody, penkb antibody, penk.L antibody, penka antibody

Background: Met-enkephalin (tyr-gly-gly-phe-met) and leu-enkephalin (tyr-gly-gly-phe-leu) are pentapeptides which compete with and mimic the effects of opiate drugs. Although interest in enkephalins stems largely from their possible role in the brain, the richest source of these peptides is the adrenal gland. The amino acid sequence shows that the precursor is 267 amino acids long and contains 6 interspersed Met-enkephalin sequences and 1 Leu-enkephalin sequence. The precursor does not contain the sequences of dynorphin, alpha-neo-endorphin or beta-endorphin. (Because of structural similarities it had been postulated that beta-endorphin is precursor of Met-enkephalin, and that dynorphin or alpha-neo-endorphin is precursor of Leu-enkephalin.)

Gene ID: 5179

Pathways: Stem Cell Maintenance