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CLEC10A antibody (Biotin)

CLEC10A Reactivity: Mouse FACS Host: Rat Monoclonal ER-MP23 Biotin
Catalog No. ABIN181063
  • Target See all CLEC10A Antibodies
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    Reactivity
    • 29
    • 10
    Mouse
    Host
    • 30
    • 4
    • 4
    • 1
    Rat
    Clonality
    • 33
    • 4
    Monoclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC10A antibody is conjugated to Biotin
    Application
    • 24
    • 23
    • 16
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognises the CD301 cell surface protein. In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Clone ER-MP23 is reported to block the function of murine CD301. The antibody binds both MGL1 and MGL2 homologues.
    Characteristics
    Synonyms: CLECSF13, CLECSF14, HML, C-type lectin domain family 10 member A, C-type lectinsuperfamily member 14, Macrophage lectin 2
    Purification
    Affinity Chromatography on Protein G
    Immunogen
    Balb/c macrophage precursor cell hybrids. Cells from immunised rats were fused with cells of the rat Y3-Ag1. 2. 3 myeloma cell line.
    Clone
    ER-MP23
    Isotype
    IgG2a
    Top Product
    Discover our top product CLEC10A Primary Antibody
  • Application Notes
    Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Lederle, Hartenstein, Meides, Kunzelmann, Werb, Angel, Mueller: "MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1175-84, (2010) (PubMed).

  • Target
    CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))
    Alternative Name
    CD301 / CLEC10A (CLEC10A Products)
    Synonyms
    CLEC10A antibody, CD301 antibody, CLECSF13 antibody, CLECSF14 antibody, HML antibody, HML2 antibody, MGL antibody, CD301a antibody, M-ASGP-BP-1 antibody, Mgl antibody, Mgl1 antibody, Mgll antibody, C-type lectin domain family 10 member A antibody, C-type lectin domain containing 10A antibody, C-type lectin domain family 10, member A antibody, LOC607405 antibody, CLEC10A antibody, Clec10a antibody
    Background
    In mice, CD301 is predominantly expressed on mature macrophages found associated with a wide range of connective tissues including macrophages in the dermis and the pancreas. Clone ER-MP23 also detects a population of dendritic cells in lymphoid tissue, which are probably recent immigrants from peripheral connective tissue sites. Expression of CD301 is induced by alternative (i.e. IL-4/IL-13 mediated) activation of macrophages and dendritic cells, but not all CD301 positive cells are necessarily IL-4/IL-13 stimulated.Synonyms: C-type lectin domain family 10 member A, C-type lectin superfamily member 14, CLECSF13, CLECSF14, HML, Macrophage lectin 2
    Gene ID
    10462
    UniProt
    Q8IUN9
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