EMR3 antibody (AA 3-97)

Catalog No. ABIN181084

Product Details anti-EMR3 Antibody

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Binding Specificity: AA 3-97

Reactivity: Human

Host: Hamster

Clonality: Monoclonal

Conjugate: This EMR3 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: This antibody recognises human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56 kDa member of the EGF-7 transmembrane (TM7) family of adhesion receptors.

Characteristics: Synonyms: EGF-Like Module-Containing Mucin-Like Receptor 3, EMR-3, EGF-like module containingmucin-like hormone receptor-like 3

Purification: Affinity chromatography on Protein G

Immunogen: ARHO-EMR3-CD97 (EGF1) transfectants. Spleen cells from immunised Armenian hamsterwere fused with cells of the mouse SP2/0 myeloma cell line. Genename: EMR3

Clone: 3D7

Isotype: IgG

Application Details

Application Notes: Immunprecipitation. Flow Cytometry: 1/25 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for EMR3

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Alternative Name: EMR3 (EMR3 Products)

Synonyms: EMR3 antibody, DKFZp459A1439 antibody, adhesion G protein-coupled receptor E3 antibody, ADGRE3 antibody, EMR3 antibody

Background: EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 Molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.Synonyms: EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3

Gene ID: 84658

UniProt: Q9BY15