CCL26 antibody

Catalog No. ABIN181151

Product Details anti-CCL26 Antibody

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL26 antibody is un-conjugated

Application: Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Specificity: Tgis antibody detects Eotaxin-3.

Characteristics: Synonyms: C-C motif chemokine 26, Small-inducible cytokine A26, SCYA26, MIP4 alpha, IMAC, TSC-1,TSC1, Macrophage inflammatory protein 4-alpha, Thymic stroma chemokine-1, CCchemokine IMAC

Purification: Affinity Chromatography on Protein A

Immunogen: Highly pure (>98%) recombinant Human Eotaxin-3

Isotype: IgG2a

Application Details

Application Notes: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman Eotaxin-3 (2 ng/mL), a concentration of 1-5 μg/mL is required. ELISA: In a sandwich ELISA (assuming 100μL/well), a concentration of 1.0-2.0 μg/mL of thisantibody will detect at least 1000 pg/mL of recombinant human Eotaxin-3 when used withBiotin conjugated anti-Human Eotaxin-3 antibody as the detection antibody at aconcentration of approximately 0.25-0.50 μg/mL. Western Blot: To detect Human Eotaxin-3 by Western Blot analysis this antibody can beused at a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatiblesecondary reagents the detection limit for recombinant hEotaxin-3 is 0.25-0.5 ng/lane,under reducing or non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore in sterile water to a concentration of 1 mg/mL.

Buffer: PBS without preservatives

Preservative: Without preservative

Storage: 4 °C/-20 °C

Storage Comment: The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2-8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CCL26

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Alternative Name: Eotaxin-3 / CCL26 (CCL26 Products)

Synonyms: CCL26 antibody, IMAC antibody, MIP-4a antibody, MIP-4alpha antibody, SCYA26 antibody, TSC-1 antibody, Ccl26l antibody, C-C motif chemokine ligand 26 antibody, chemokine (C-C motif) ligand 26 antibody, CCL26 antibody, Ccl26 antibody

Background: Eotaxin 3 is a recently discovered CC chemokine. It binds to the CCR3 receptor and is highly chemotactic for eosinophils and basophils.Synonyms: C-C motif chemokine 26, CC chemokine IMAC, IMAC, MIP4 alpha, Macrophage inflammatory protein 4-alpha, SCYA26, Small-inducible cytokine A26, TSC-1, TSC1, Thymic stroma chemokine-1

Gene ID: 10344

UniProt: Q9Y258

Pathways: Regulation of Actin Filament Polymerization