You are viewing an incomplete version of our website. Please click to reload the website as full version.

VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (C-Term)

Details for Product anti-KDR Antibody No. ABIN181334, Supplier: Log in to see
Antigen
  • vegfr-2
  • KDR
  • 6130401C07
  • Flk-1
  • Flk1
  • Krd-1
  • Ly73
  • VEGFR-2
  • VEGFR2
  • sVEGFR-2
  • Vegfr-2
  • CD309
  • FLK1
  • VEGFR
  • FLK-1
  • flk-1
  • FLK/KDR
  • flk1
  • flk1b
  • kdrb
  • si:busm1-205d10.1
  • si:ch211-254j6.1
  • si:ch211-278f21.4
  • wu:fc31a09
  • fk52c05
  • flk
  • kdr
  • kdra
  • vegfr2
  • vegfr4
  • vegr2
  • wu:fk52c05
Alternatives
anti-Human VEGFR2 antibody for Immunohistochemistry (Frozen Sections)
Epitope
C-Term
61
49
47
33
24
18
17
16
16
14
13
13
12
12
12
12
9
8
6
6
6
6
5
5
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
485
227
134
5
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
437
96
23
2
2
1
1
Clonality
Polyclonal
Conjugate
This VEGFR2 antibody is un-conjugated
33
21
16
14
12
11
3
3
3
3
3
3
3
3
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
373
227
194
100
95
78
28
23
22
20
17
16
8
6
5
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen A synthetic peptide from C-terminus of the precursor form of the Mouse Flk-1
Specificity This antibody detects CD309/VEGFR-2/Flk-1.
Cellular Localization: Cytoplasmic.
Purification Protein A Chromatography
Alternative Name CD309 / VEGFR-2 / Flk-1 (KDR Antibody Abstract)
Background Flk-1/KDR/Vascular Endothelial Growth Factor Receptor 2, a cell membrane receptor kinase, is a high affinity receptor for vascular endothelial growth factor and is putatively involved in the growth of endothelial cells and angiogenesis. It contains seven immunoglobulin like sequences in the extracellular domain and exhibits sequence similarity to Flt-1 and Flt-4.Synonyms: FLK1, KDR, Kinase NYK, Kinase insert domain receptor, Protein-tyrosine kinase receptor Flk-1, VEGF Receptor 2, VEGFR2, Vascular endothelial growth factor receptor 2
Gene ID 3791
NCBI Accession NP_002244
UniProt P35968
Research Area Cytokines, Receptors
Pathways RTK Signaling
Application Notes Western Blotting: 5-10 μg/mL for 2h at RT. Immunohistochemistry (Formalin/Paraffin): Use VEGFR2 antibody at 1/50 for 60 min at RT. Staining of formalin-fixed tissues Requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive Control: Hey Cells, Angiosarcoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer 10 mM PBS, pH 7.4, 0.09 % Sodium Azide, 0.2 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (C-Term) (ABIN181334) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody
 image for anti-VEGFR2 antibody (Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase)) (C-Term) (ABIN181334) anti-Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (C-Term) antibody (Image 2)
Background publications Ankoma-Sey, Matli, Chang et al.: "Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing." in: Oncogene, Vol. 17, Issue 1, pp. 115-21, 1998 (PubMed).

Ergün, Kiliç, Fiedler et al.: "Vascular endothelial growth factor and its receptors in normal human testicular tissue." in: Molecular and cellular endocrinology, Vol. 131, Issue 1, pp. 9-20, 1997 (PubMed).

Quinn, Peters, De Vries et al.: "Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 16, pp. 7533-7, 1993 (PubMed).

Millauer, Wizigmann-Voos, Schnürch et al.: "High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis." in: Cell, Vol. 72, Issue 6, pp. 835-46, 1993 (PubMed).