»
Antibodies
»
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC1...
X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC1) antibody
| Antigen |
|
| Synonyms |
DKFZp781P0919, RecA, RAD51, 4921524O04Rik, 8030409M04Rik, XRCC2, RGD1564823, MGC160004 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
|
| Catalog no. |
ABIN181348 |
| Quantity |
0.5 mg (1 mg/ml) (Variants) |
| Price |
550.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: DNA repair protein XRCC2, X-ray repair cross-complementing protein 2
|
|
Alternative name
|
XRCC2
|
|
Swiss-Prot
|
O43543
|
|
Immunogen
|
A synthetic peptide derived from the N-terminus of human XRCC2 protein. Remarks: Mol. Wt. of Antigen: 32 kDa
|
|
Description
|
XRCC2 (X-Ray Cross Complementing 2) is essential for repairing the double srand DNAbreaks by homologous recombination between sister chromatids. It is homologous toRad51. Five human homologues of RAD 51, XRCC2, XRCC3, RAD51B, RAD51C, RAD51D,interact among themselves to form one big complex or several smaller complexes.
|
|
Specificity
|
This antibody detects XRCC2. Cellular Localization: Nuclear and cytoplasmicSpecies: Human. Others not tested.
|
|
Application Notes
|
Western Blotting: Ab 5-10 ug/ml for 2 hrs at RT. Immunohistology (formalin/paraffin): Ab 10-20 ug/ml for 30 min at RT. Staining offormalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for10-20 min followed by cooling at RT for 20 min. Recommended positive control: HT29 orHeLa cells. Testis. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1 mg/ml
|
|
Buffer
|
10 mM PBS, pH 7.4, with 0.2 % BSA & 0.09 % sodium azide.
|
|
Storage
|
Store the antibody at 4-8 °C for one month or at -20 °C for longer. Avoid repeated freezingand thawing. Shelf life: one year from despatch.
|
|
Research Area
|
Chromatin and Nuclear Signaling, DNA/RNA
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 2 (XRCC1)", type "Antibodies"
