»
Antibodies
»
anti-Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) antibody
Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A) antibody
| Antigen |
|
| Synonyms |
CAMKA, KIAA0968, CaMKII, R74975, mKIAA0968, PKCCD, PK2CDD, CAMK2A, MGC139375, MGC155201, MGC123320, zgc:112538, zgc:123320, DKFZp459L1326 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
 Alternatives Amphibian, Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
Human (35), Rat (Rattus) (24), Mouse (Murine) (17), Cow (Bovine) (6), Xenopus laevis (3), Dog (Canine) (2), Rabbit (2), Chicken (1), Guinea Pig (1), Hamster (1), Monkey (1), Pig (Porcine) (1)
|
|
Application
|
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
Western Blotting (WB) (45), Immunofluorescence (IF) (13), ELISA (12), Enzyme Immunoassay (EIA) (12), Immunoprecipitation (IP) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (IHC) (8), Radioimmunoassay (RIA) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), ELISA (Detection) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1)
|
| Catalog no. |
ABIN181534 |
| Quantity |
50 µg (1.0mg/ml) (Variants) |
| Price |
700.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 7 to 10 Business Days |
|
Characteristics
|
Synonyms: CAMKA, KIAA0968, CaM-kinase II alpha chain, CaM kinase II subunit alpha, CaMK-IIsubunit alpha, Calcium/calmodulin-dependent protein kinase type II alpha chain
|
|
Alternative name
|
CAMK2A
|
|
Swiss-Prot
|
Q9UQM7
|
|
Immunogen
|
Synthetic peptide corresponding to amino acids 6-23 of human CaMKII.
|
|
Description
|
CaMKII is a serine/threonine kinase that is activated by calcium ions (Ca2+) and theCa2+/calmodulin complex (CaM). CaMKII is expressed in glutamatergic excitatoryneurones and constitutes the major postsynaptic density protein. It is important in theregulation of synaptic transmission, with possible roles in learning and memory. CaMKIIcomprises multiple isoforms that are derived from four closely related gene products,alpha, beta, gamma and delta, that have distinct but overlapping expression patterns. Decreased alpha CaMKII autophosphorylation capability in the hippocampus is associatedwith Angelman syndrome, which is associated with mental retardation.
|
|
Specificity
|
This antibody detects calcium/calmodulin-dependent protein kinase II (CaMKII). Species: Human. Others not tested.
|
|
Application Notes
|
ELISA: 1: 4000 - 1: 20000. Western Blot: 1: 1000 - 1: 3000, this antibody detects a band of approximately 54kDa inmouse brain cell lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
|
|
Concentration
|
1.0mg/ml
|
|
Buffer
|
PBS, pH 7.2 containing 0.01% Sodium Azide
|
|
Storage
|
Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
|
|
Research Area
|
Kinases/Phosphatases
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A)", type "Antibodies"
|
Hosts
|
Rabbit (23), Mouse (20), Goat (4)
|
|
Reactivities
|
Human (35), Rat (Rattus) (24), Mouse (Murine) (17), Cow (Bovine) (6), Xenopus laevis (3), Dog (Canine) (2), Rabbit (2), Chicken (1), Guinea Pig (1), Hamster (1), Monkey (1), Pig (Porcine) (1)
|
|
Applications
|
Western Blotting (WB) (45), Immunofluorescence (IF) (13), ELISA (12), Enzyme Immunoassay (EIA) (12), Immunoprecipitation (IP) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunohistochemistry (IHC) (8), Radioimmunoassay (RIA) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), ELISA (Detection) (3), Dot Blot (Dot) (1), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1)
|
|
Epitopes
|
pThr286 (8), C-Term (1), C-Term E370 (1)
|
