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Macrophage Scavenger Receptor 1 antibody (PE)

MSR1 Reactivity: Mouse FACS Host: Rat Monoclonal 2F8 PE
Catalog No. ABIN181781
  • Target See all Macrophage Scavenger Receptor 1 (MSR1) Antibodies
    Macrophage Scavenger Receptor 1 (MSR1)
    Reactivity
    • 62
    • 58
    • 18
    • 16
    • 8
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Mouse
    Host
    • 60
    • 16
    • 5
    Rat
    Clonality
    • 59
    • 18
    Monoclonal
    Conjugate
    • 33
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Macrophage Scavenger Receptor 1 antibody is conjugated to PE
    Application
    • 61
    • 35
    • 30
    • 14
    • 13
    • 13
    • 12
    • 10
    • 9
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognises the murine scavenger receptor class A (SRA), type I and II, also known as CD204. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recent research shows that clone 2F8 recognises an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
    Purification
    Affinity chromatography on Protein G
    Immunogen
    RAW264 cell line. Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.
    Clone
    2F8
    Isotype
    IgG2b
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  • Application Notes
    Flow Cytometry: The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 1 mL distilled water.
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Preservative
    Sodium azide
    Precaution of Use
    Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    Macrophage Scavenger Receptor 1 (MSR1)
    Alternative Name
    CD204 (MSR1 Products)
    Synonyms
    CD204 antibody, SCARA1 antibody, SR-A antibody, SRA antibody, phSR1 antibody, phSR2 antibody, MRS-A antibody, MSR antibody, MSR-A antibody, SR-AI antibody, SR-AII antibody, Scara1 antibody, Scvr antibody, MSR1 antibody, RGD1564316 antibody, macrophage scavenger receptor 1 antibody, scavenger receptor class A member 5 antibody, MSR1 antibody, Msr1 antibody, SCARA5 antibody
    Background
    CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.Synonyms: MSR1, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, Scavenger receptor class A member 1
    Gene ID
    20288
    NCBI Accession
    NP_001106797
    UniProt
    P30204
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