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Macrophage Mannose Receptor 1 antibody (Biotin)

MRC1 Reactivity: Mouse FACS Host: Rat Monoclonal MR5D3 Biotin
Catalog No. ABIN181884
  • Target See all Macrophage Mannose Receptor 1 (MRC1) Antibodies
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Reactivity
    • 62
    • 37
    • 23
    • 16
    • 1
    • 1
    Mouse
    Host
    • 43
    • 21
    • 11
    Rat
    Clonality
    • 41
    • 30
    Monoclonal
    Conjugate
    • 34
    • 8
    • 8
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Macrophage Mannose Receptor 1 antibody is conjugated to Biotin
    Application
    • 53
    • 39
    • 23
    • 16
    • 13
    • 11
    • 9
    • 8
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody recognises the mannose receptor, a 175 kDa type 1 membrane protein that is also known as CD206. Clone MR5D3 has been reported to be non-inhibitory for the binding of the mannose receptor to carbohydrate ligands.
    Purification
    Affinity chromatography on Protein G
    Immunogen
    Chimaeric CRD4-7-Fc protein. Spleen cells from immunised Fischer rats were fused with cells of the Y3 myeloma cell line.
    Clone
    MR5D3
    Isotype
    IgG2a
    Top Product
    Discover our top product MRC1 Primary Antibody
  • Application Notes
    Flow Cytometry: Neat - 1/10, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.1 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Terminel, Bassil, Rau, Trevino, Ruiz, Alaniz, Hook: "Morphine-induced changes in the function of microglia and macrophages after acute spinal cord injury." in: BMC neuroscience, Vol. 23, Issue 1, pp. 58, (2022) (PubMed).

  • Target
    Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
    Alternative Name
    CD206 / MRC1 (MRC1 Products)
    Synonyms
    CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mrc1 antibody, MGC86525 antibody, MRC1 antibody, MRC1L-A antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, mannose receptor C-type 1 L homeolog antibody, mediator of replication checkpoint 1 antibody, MRC1 antibody, Mrc1 antibody, mrc1.L antibody, mrc1 antibody
    Background
    CD206 is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.Synonyms: C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, CLEC13D, CLEC13DL, MRC1L1, Macrophage mannose receptor, Macrophage mannose receptor 1-like protein 1
    Gene ID
    17533
    NCBI Accession
    NP_032651
    UniProt
    Q61830
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