KIT Ligand antibody

Catalog No. ABIN1819330

Product Details anti-KIT Ligand Antibody

Target: KIT Ligand (KITLG)

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIT Ligand antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Specificity: Recognizes rat stem cell factor (SCF), a type I transmembrane protein and hematopoietic growth factor which acts in synergy with other growth factors, and signals through the receptor tyrosine kinase c-Kit (CD117). The interaction between SCF and c-Kit regulates developmental and functional processes of hematopoietic progenitor cells, mast cells, melanocytes and germ cells, and plays an important role in follicular development. The interaction between SCF and c-Kit is associated with the progression and invasiveness of some tumors, including melanomas.

Purification: Affinity purified

Immunogen: Recombinant rat SCF.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: ELISA (0.5 - 2 μg/mL), Func (0.08 - 0.12 μg/mL), WB (0.1 - 0.2 μg/mL)

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: PBS

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Target Details for KIT Ligand

Target: KIT Ligand (KITLG)

Alternative Name: KITLG / SCF (KITLG Products)

Synonyms: Xkl-1 antibody, Xsl antibody, Xsl-1 antibody, Xsl-2 antibody, steel antibody, KITLG antibody, SCF antibody, kitl antibody, kl-1 antibody, mgf antibody, scf antibody, FPH2 antibody, KL-1 antibody, Kitl antibody, MGF antibody, SF antibody, SHEP7 antibody, Clo antibody, Con antibody, Gb antibody, Kitlg antibody, Mgf antibody, SLF antibody, Sl antibody, blz antibody, contrasted antibody, 710-712 antibody, CSF antibody, KITL antibody, KIT ligand L homeolog antibody, KIT ligand antibody, kit ligand antibody, kitlg.L antibody, KITLG antibody, kitlg antibody, Kitl antibody, Kitlg antibody

Background: Name/Gene ID: KITLG

Synonyms: KITLG, C-Kit ligand, KIT ligand, Kitl, KL-1, SHEP7, SF, Steel factor, Stem cell factor, SCF, FPH2, Mast cell growth factor, MGF

Gene ID: 4254

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway