Caudal Type Homeobox 2 (CDX2) (Middle Region) antibody

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Antigen
Synonyms CDX2, MGC130987, cdx3-like, CDX-3, CDX3, CDX-2, Cdx-2
Epitope
Middle Region
(40), (26), (15), (14), (13), (11), (9), (6), (6), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
(191), (54), (51), (7), (6), (3), (1), (1), (1), (1)
Host
Rabbit
(120), (52), (21)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (5), (5), (5), (5), (5), (1)
Application
Western Blotting (WB)
(140), (97), (38), (36), (20), (20), (20), (18), (11), (5), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human CDX2
Blocking Peptide Blocking peptide for this product available: Caudal Type Homeobox 2 (CDX2) peptide (ABIN974800)
Sequence QRRNLCEWMR KPAQQSLGSQ VKTRTKDKYR VVYTDHQRLE LEKEFHYSRY
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against CDX2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CDX2 (CDX2 Antibody Abstract)
Background CDX2 encodes a protein that plays an important role in gallbladder carcinogenesis with intestinal differentiation. Cdx2 is a highly sensitive marker for Barrett's esophagus.
Molecular Weight 34 kDa
Gene ID 1045
NCBI Accession NP_001256, NM_001265
UniProt Q99626
Research Area Transcription Factors, Lineage Markers, CD Antigens, Surface Receptors of Immune Cells
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 313 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Caudal Type Homeobox 2 (CDX2) (Middle Region) antibody (ABIN182373) WB Suggested Anti-CDX2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Product cited in: Bell, Watson: "p38 MAPK regulates cavitation and tight junction function in the mouse blastocyst." in: PLoS ONE, Vol. 8, Issue 4, pp. e59528, 2013 (PubMed).

Background publications Saad, Cho, Silverman et al.: "Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma." in: American journal of clinical pathology, Vol. 122, Issue 3, pp. 421-7, 2004 (PubMed).

Catalog No. ABIN182373
$289.00
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