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Details for Product No. ABIN182460

Visual System Homeobox 2 (VSX2) (C-Term) antibody

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Antigen
Synonyms RET1, CHX10, HOX10, MCOP2, MCOPCB3, or, Chx10, Hox10, Hox-10, VSX2, Vsx-2, alx, chx10
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN182460
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-CHX10 antibody: synthetic peptide directed towards the C terminal of human CHX10
Sequence ESILKSAKDGIMDSCAPWLLGMHKKSLEAAAESGRKPEGE RQALPKLDKM
Predicted Reactivity Rat : 92%
Characteristics This is a rabbit polyclonal antibody against CHX10. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name CHX10
Background Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina. The strong conservation in vertebrates of the CHX10 sequence, pattern of expression and loss-of-function phenotypes demonstrates the evolutionary importance of the genetic network through which this gene regulates eye development.
Molecular Weight 39kDa
Gene ID 338917
NCBI Accession NP_878314, NM_182894
UniProt P58304
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-CHX10 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Ferda Percin, Ploder, Yu et al.: "Human microphthalmia associated with mutations in the retinal homeobox gene CHX10." in: Nature genetics, Vol. 25, Issue 4, pp. 397-401, 2000 (PubMed).

Alternatives for antigen "Visual System Homeobox 2 (VSX2)", type "Antibodies"
Hosts (25), (12), (1)
Reactivities (24), (23), (21), (15), (12), (12), (1), (1)
Applications (28), (11), (10), (6), (4), (3), (3), (3), (1)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (3), (2), (2), (2), (1), (1)
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