Visual System Homeobox 2 (VSX2) (C-Term) antibody

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Antigen
Synonyms VSX2, CHX10, c-ret, cret, etID315074.13, ret1, wu:fd13h01, HOX10, MCOP2, MCOPCB3, RET1, Chx10, Hox-10, Hox10, or, Vsx-2, alx, chx10
Epitope
C-Term
(25), (16), (12), (7), (3), (2), (2), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine)
(36), (14), (13), (9), (3)
Host
Rabbit
(53), (9), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (5), (2), (2), (2), (2), (1)
Application
Western Blotting (WB)
(47), (33), (5), (4), (4), (3), (2), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human CHX10
Blocking Peptide Blocking peptide for this product available: Visual System Homeobox 2 (VSX2) peptide (ABIN974983)
Sequence ESILKSAKDG IMDSCAPWLL GMHKKSLEAA AESGRKPEGE RQALPKLDKM
Predicted Reactivity Rat : 92 %
Characteristics This is a rabbit polyclonal antibody against CHX10. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CHX10 (VSX2 Antibody Abstract)
Background Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina. The strong conservation in vertebrates of the CHX10 sequence, pattern of expression and loss-of-function phenotypes demonstrates the evolutionary importance of the genetic network through which this gene regulates eye development.
Molecular Weight 39 kDa
Gene ID 338917
NCBI Accession NM_182894, NP_878314
UniProt P58304
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 361 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Visual System Homeobox 2 (VSX2) (C-Term) antibody (ABIN182460) WB Suggested Anti-CHX10 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Ferda Percin, Ploder, Yu et al.: "Human microphthalmia associated with mutations in the retinal homeobox gene CHX10." in: Nature genetics, Vol. 25, Issue 4, pp. 397-401, 2000 (PubMed).

Catalog No. ABIN182460
$289.00
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