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Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody

Details for Product No. ABIN182483
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Antigen
Synonyms H2TF1, LYT-10, LYT10, NF-kB2, p105, p52, RGD1307189, ebp-1, kbf1, nf-kappa-b, nf-kappaB, nfkb-p105, nfkb-p50
Epitope
C-Term
(15), (15), (10), (9), (7), (7), (6), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human
(103), (41), (27), (3), (1), (1), (1)
Host
Rabbit
(102), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(92), (38), (34), (25), (22), (20), (10), (9), (3), (3), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN182483
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the C terminal of human NFKB2
Sequence SDSDSDSEGPEKDTRSSFRGHTPLDLTCSTLVKTLLLNAA QNTMEPPL
Predicted Reactivity Human : 100 %, Rabbit : 90 %, Horse : 80 %, Bovine : 70 %
Characteristics This is a rabbit polyclonal antibody against NFKB2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name NFKB2
Background NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Molecular Weight 101 kDa
Gene ID 4791
NCBI Accession NM_002502, NP_002493
UniProt Q00653
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 933 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody WB Suggested Anti-NFKB2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody (2) anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody (Image 2)
anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody (3) anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) (C-Term) antibody (Image 3)
Background publications Xiao, Fong, Sun: "Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30099-105, 2004 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN182483
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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