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Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) antibody

Antigen

Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2)
Synonyms
p50, KBF1, p105, EBP-1, MGC54151, NFKB-p50, NF-kappaB, NFKB-p105, NF-kappa-B, DKFZp686C01211, p52, LYT10, LYT-10, NF-kB, NF-KB1, NFKB1, kbf1, ebp-1, MGC86262, nfkb-p50, nf-kappaB, nfkb-p105, nf-kappa- ... show more
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Cow (Bovine), Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
1 reference available
Catalog no. ABIN182483
Quantity 50 µg  (Variants)
Price 317.90 $   Plus shipping costs $45.00
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anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) antibody

anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) antibody (2)

anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2) antibody (3)

Additional Information
Application Details Publications Images Alternatives Variants back to top

Alternative name NFKB2 / NF-kappa-B p100/p52
Gene ID NFKB2
UniProt Q00653
Immunogen The immunogen for anti-NFKB2 antibody: synthetic peptide directed towards the C terminal of human NFKB2
Sequence SDSDSDSEGPEKDTRSSFRGHTPLDLTCSTLVKTLLLNAA QNTMEPPL
Cross-Reactivity Cow (Bovine), Human
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-NFKB2 antibody concentration is 1 mg/ml.
Description NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Characteristics Antigen Size: 933 amino acids
Molecular Weight 101kDa
Synonyms p50, KBF1, p105, EBP-1, MGC54151, NFKB-p50, NF-kappaB, NFKB-p105, NF-kappa-B, DKFZp686C01211, p52, LYT10, LYT-10, NF-kB, NF-KB1, NFKB1, kbf1, ebp-1, MGC86262, nfkb-p50, nf-kappaB, nfkb-p105, nf-kappa-b, NFKB2, MGC179374

Application Details
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Application Notes WB Suggested Anti-NFKB2 Antibody Titration: 0.2-1 ug/ml
Positive Control: Jurkat cell lysate.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Restrictions For Research Use only

Publications
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Product Xiao, Fong, Sun: "Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30099-105, 2004 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (NFKB2)", type "Antibodies"
Hosts Rabbit (102), Mouse (6)
Reactivities Human (104), Mouse (Murine) (80), Rat (Rattus) (65), Cow (Bovine) (43), Chicken (42), Dog (Canine) (42), Pig (Porcine) (38), Horse (Equine) (18), Cat (Feline) (4), Rabbit (1)
Applications Western Blotting (WB) (66), Immunofluorescence (IF) (61), Immunohistochemistry (IHC) (35), ELISA (30), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (21), Immunoprecipitation (IP) (21), Immunocytochemistry (ICC) (7), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (6), Immunoelectron Microscopy (IEM) (2), Dot Blot (DB) (1), Dot Blot (Dot) (1), Gel Shift (GS) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (4), Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy5.5 (2), Alexa Flour 488 (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1), Un-conjugated (1)
Epitopes C-Term (5), N-Term (5), pSer870,pSer866 (4), Ser869 (3), pSer865 (3), AA 1-19 (2), AA 4-19 (2), pSer866 (2), AA 1-447 (1), Middle Region (1), Ser61 (1), pSer222 (1), pSer869 (1)