Sirtuin 6 (SIRT6) (N-Term) antibody

Details for Product No. ABIN182566
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Antigen
Synonyms SIR2L6, 2810449N18Rik, AI043036, Sir2l6
Epitope
N-Term
(39), (12), (8), (7), (7), (6), (5), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine), Xenopus laevis, Human, Chicken
(101), (38), (29), (3), (1), (1)
Host
Rabbit
(100), (8), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(10), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(88), (40), (25), (23), (20), (8), (6), (6), (3), (3), (3), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN182566
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human SIRT6
Sequence STASGIPDFR GPHGVWTMEE RGLAPKFDTT FESARPTQTH MALVQLERVG
Predicted Reactivity Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Bovine : 90 %, Guinea pig : 90 %, Horse : 90 %, Rat : 90 %, African clawed frog : 80 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against SIRT6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name SIRT6
Background SIRT6 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by SIRT6 is included in class IV of the sirtuin family.
Molecular Weight 39 kDa
Gene ID 51548
NCBI Accession NP_057623, NM_016539
UniProt Q8N6T7
Research Area Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 355 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Sirtuin 6 (SIRT6) (N-Term) antibody WB Suggested Anti-SIRT6 Antibody Titration: 1.25ug/ml
Positive Control: HepG2 cell lysate
anti-Sirtuin 6 (SIRT6) (N-Term) antibody (2) anti-Sirtuin 6 (SIRT6) (N-Term) antibody (Image 2)
anti-Sirtuin 6 (SIRT6) (N-Term) antibody (3) U2OS
anti-Sirtuin 6 (SIRT6) (N-Term) antibody (4) WB Suggested Anti-SIRT6
Antibody Titration: 1.25 µg/mL
Positive Control: HepG2 cell lysate
Background publications Frye: "Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins." in: Biochemical and biophysical research communications, Vol. 273, Issue 2, pp. 793-8, 2000 (PubMed).

Validation Images
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