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Details for Product No. ABIN182574

Paired Box 3 (PAX3) (Middle Region) antibody

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Antigen
Synonyms CDHS, HUP2, WS1, WS3, pax3, zgc:92547, PAX3, cdhs, hup2, pax-3, ws1, xpax3
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Xenopus laevis, Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN182574
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-PAX3 antibody: synthetic peptide directed towards the middle region of human PAX3
Sequence KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDE GSDIDSEPDL
Predicted Reactivity Bovine : 100%, Dog : 100%, Goat : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Rabbit : 100%, Rat : 100%, Chicken : 92%
Characteristics This is a rabbit polyclonal antibody against PAX3. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name PAX3
Background PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.
Molecular Weight 45kDa
Gene ID 5077
NCBI Accession NP_852126, NM_181461
UniProt Q86UQ3
Research Area Organogenesis, Lineage Markers, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-PAX3 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Wachtel, Dettling, Koscielniak et al.: "Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1." in: Cancer research, Vol. 64, Issue 16, pp. 5539-45, 2004 (PubMed).

Alternatives for antigen "Paired Box 3 (PAX3)", type "Antibodies"
Hosts (36), (17), (8)
Reactivities (56), (27), (20), (3), (3), (2), (2), (1), (1)
Applications (41), (23), (13), (10), (9), (3), (3), (3), (2), (2), (1), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (5), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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