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WWTR1 antibody (N-Term)

WWTR1 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN182600
  • Target See all WWTR1 Antibodies
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Binding Specificity
    • 11
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 38
    • 16
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit
    Host
    • 34
    • 4
    Rabbit
    Clonality
    • 34
    • 4
    Polyclonal
    Conjugate
    • 23
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WWTR1 antibody is un-conjugated
    Application
    • 31
    • 16
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PRLAGGAQHV RSHSSPASLQ LGTGAGAAGS PAQQHAHLRQ QSYDVTDELP
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against WWTR1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human WWTR1
    Top Product
    Discover our top product WWTR1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 400 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))
    Alternative Name
    WWTR1 (WWTR1 Products)
    Synonyms
    WWTR1 antibody, TAZ antibody, 2310058J06Rik antibody, 2610021I22Rik antibody, C78399 antibody, Taz antibody, WW domain containing transcription regulator 1 L homeolog antibody, WW domain containing transcription regulator 1 antibody, wwtr1.L antibody, wwtr1 antibody, WWTR1 antibody, Wwtr1 antibody
    Background
    TAZ (transctiptional coactivator with PDZ-binding motif), also known as WW domain containing transcription regulator 1 (WWTR1), is a member of the bicoid sub-family of homeodomain-containing transcription factors. TAZ is a 14-3-3 binding protein that co-activates Runx2-dependent gene transcription while repressing PPAR-gamma-dependent gene transcription. TAZ has been reported to be a modulator of mesenchymal stem cell differentiation. TAZ may also play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
    Alias Symbols: DKFZP586I1419, TAZ
    Protein Interaction Partner: MED28, NOTCH1, YWHAQ, LATS1, BTRC, YWHAE, TP53BP2, PPP1CA, KLF5, YWHAZ, YWHAG, PAX3, SLC9A3R2, TEAD3, TEAD4, NKX2-1, RUNX1,
    Protein Size: 400
    Molecular Weight
    44 kDa
    Gene ID
    25937
    NCBI Accession
    NM_015472, NP_056287
    UniProt
    Q9GZV5
    Pathways
    Regulation of Lipid Metabolism by PPARalpha
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