anti-Retinoblastoma 1 antibody (RB1) (C-Term)

Details for Product anti-RB1 Antibody No. ABIN182758, Supplier: Login to see New
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Antigen
Synonyms RB1, OSRC, RB, p105-Rb, pRb, pp110, Rb, Rb-1, zgc:154147, P105-RB, PP110, RB11
Alternatives
Epitope
C-Term
(55), (53), (50), (42), (35), (28), (26), (21), (17), (17), (16), (13), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(540), (266), (242), (10), (8), (7), (4), (4), (4), (4), (3), (2), (2), (2)
Host
Rabbit
(480), (69), (3)
Clonality
Polyclonal
Conjugate
This Retinoblastoma 1 antibody is un-conjugated
(22), (20), (20), (15), (13), (13), (10), (9), (9), (7), (7), (7), (7), (7), (7)
Application
Western Blotting (WB)
(336), (220), (183), (83), (82), (76), (44), (35), (16), (13), (10), (8), (6), (5), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human RB1
Blocking Peptide Blocking peptide for this product available: Retinoblastoma 1 (RB1) peptide (ABIN982700)
Sequence IMMCSMYGIC KVKNIDLKFK IIVTAYKDLP HAVQETFKRV LIKEEEYDSI
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against RB1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RB1 (RB1 Antibody Abstract)
Background Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Molecular Weight 106 kDa
Gene ID 5925
NCBI Accession NM_000321, NP_000312
UniProt P06400
Pathways Cell Division Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 928 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Retinoblastoma 1 antibody (RB1) (C-Term) (ABIN182758) WB Suggested Anti-RB1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1...
Background publications Dasgupta, Sun, Wang et al.: "Disruption of the Rb--Raf-1 interaction inhibits tumor growth and angiogenesis." in: Molecular and cellular biology, Vol. 24, Issue 21, pp. 9527-41, 2004 (PubMed).

Catalog No. ABIN182758
$289.00
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