SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (C-Term) antibody

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Antigen
Epitope
C-Term
(8), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(31), (11), (7), (2)
Host
Rabbit
(28), (6)
Clonality
Polyclonal
Application
Western Blotting (WB)
(32), (9), (8), (7), (6), (5), (3), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the C terminal of human SMARCC1
Sequence TKSEEKETEE NKELTDTCKE RESDTGKKKV EHEISEGNVA TAAAAALASA
Predicted Reactivity Human : 100 %, Rat : 100 %, Bovine : 90 %, Dog : 90 %, Horse : 90 %, Mouse : 90 %, Pig : 90 %, Guinea pig : 80 %, Chicken : 70 %
Characteristics This is a rabbit polyclonal antibody against SMARCC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name SMARCC1 (SMARCC1 Antibody Abstract)
Background SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
Molecular Weight 123 kDa
Gene ID 6599
NCBI Accession NP_003065, NM_003074
UniProt Q92922
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1105 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) (C-Term) antibody (ABIN182775) WB Suggested Anti-SMARCC1 Antibody Titration: 1.25ug/ml
ELISA Titer:
Background publications Phelan, Sif, Narlikar et al.: "Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits." in: Molecular cell, Vol. 3, Issue 2, pp. 247-53, 1999 (PubMed).

Catalog No. ABIN182775
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