T-Box 5 antibody (Middle Region)

Catalog No. ABIN182797

Product Details anti-T-Box 5 Antibody

Target: T-Box 5 (TBX5)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RMQSKEYPVV PRSTVRQKVA SNHSPFSSES RALSTSSNLG SQYQCENGVS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TBX5. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5 (TBX5 Products)

Synonyms: TBX5 antibody, tbx-5 antibody, xtbx-5 antibody, xtbx5 antibody, tbx5 antibody, HOS antibody, tbx5.1 antibody, zTbx5 antibody, zf-tbx5 antibody, T-box 5 antibody, T-box 5 L homeolog antibody, T-box 5a antibody, TBX5 antibody, tbx5 antibody, tbx5.L antibody, Tbx5 antibody, tbx5a antibody

Background: TBX5 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The encoded protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs.
Alias Symbols: HOS
Protein Interaction Partner: KDM6A, SMARCA4, KAT5, GATA4, NKX2-5,
Protein Size: 349

Molecular Weight: 39 kDa

Gene ID: 6910

NCBI Accession: NM_080718, NP_542449