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PARP16 antibody (N-Term)

PARP16 Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Pig, Rabbit, Cow, Dog WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN182872
  • Target See all PARP16 Antibodies
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 36
    • 20
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    Human, Mouse, Rat, Guinea Pig, Horse, Pig, Rabbit, Cow, Dog
    Host
    • 35
    • 1
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PARP16 antibody is un-conjugated
    Application
    • 34
    • 15
    • 13
    • 13
    • 13
    • 5
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KRDSVLRPFP ASYARGDCKD FEALLADASK LPNLKELLQS SGDNHKRAWD
    Predicted Reactivity
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against PARP16. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PARP16
    Top Product
    Discover our top product PARP16 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 323 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
    Alternative Name
    PARP16 (PARP16 Products)
    Synonyms
    PARP16 antibody, zgc:77744 antibody, ARTD15 antibody, C15orf30 antibody, pART15 antibody, BC055447 antibody, C79952 antibody, PARP-16 antibody, LRRGT00109 antibody, RGD1306243 antibody, poly(ADP-ribose) polymerase family member 16 antibody, poly(ADP-ribose) polymerase family member 16 L homeolog antibody, poly (ADP-ribose) polymerase family, member 16 antibody, PARP16 antibody, parp16.L antibody, parp16 antibody, Parp16 antibody
    Background
    Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP16 is a member of poly(ADP-ribose) polymerases (PARPs) family that is encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins.
    Alias Symbols: pART15, C15orf30
    Protein Interaction Partner: GMCL1, UBC, NEDD4,
    Protein Size: 323
    Molecular Weight
    36 kDa
    Gene ID
    54956
    NCBI Accession
    NM_017851, NP_060321
    UniProt
    Q6PK64
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