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PHD1 antibody (N-Term)

EGLN2 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN183017
  • Target See all PHD1 (EGLN2) Antibodies
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 59
    • 31
    • 16
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Pig
    Host
    • 70
    • 3
    • 1
    Rabbit
    Clonality
    • 66
    • 8
    Polyclonal
    Conjugate
    • 30
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHD1 antibody is un-conjugated
    Application
    • 63
    • 35
    • 16
    • 14
    • 13
    • 9
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    SAGSGTPRAT ATSTTASPLR DGFGGQDGGE LRPLQSEGAA ALVTKGCQRL
    Predicted Reactivity
    Cow: 79%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 79%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against EGLN2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EGLN2
    Top Product
    Discover our top product EGLN2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 407 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
    Alternative Name
    EGLN2 (EGLN2 Products)
    Synonyms
    egln2 antibody, phd2 antibody, PHD1 antibody, 0610011A13Rik antibody, C85656 antibody, Hif-p4h-1 antibody, Ier4 antibody, Phd1 antibody, SM-20 antibody, HIF-PH1 antibody, HPH-1 antibody, HPH-3 antibody, PHD-1 antibody, EIT6 antibody, HIFPH1 antibody, egl-9 family hypoxia-inducible factor 1 antibody, egl-9 family hypoxia inducible factor 2 antibody, Egl nine homolog 2 antibody, egl-9 family hypoxia-inducible factor 2 L homeolog antibody, egl-9 family hypoxia-inducible factor 2 antibody, egln1 antibody, EGLN2 antibody, egln2 antibody, egln2.L antibody, Egln2 antibody
    Background
    The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. EGLN2 encodes an enzyme responsible for this posttranslational modification. Alternative splicing of EGLN2 results in three transcript variants encoding different isoforms.
    Alias Symbols: EIT6, PHD1, HPH-1, HPH-3, HIFPH1, HIF-PH1
    Protein Interaction Partner: SRPK2, CEP192, IKBKG, FAM46A, EPAS1, A2M, MAGEA11, SIAH2, LPP, WTIP, AJUBA, LIMD1, TRIP6, SPRY2, PRPF19, EGLN3, EGLN2, HIF1A, HIF3A, MOB4, POLR2A,
    Protein Size: 407
    Molecular Weight
    44 kDa
    Gene ID
    112398
    NCBI Accession
    NM_053046, NP_444274
    UniProt
    Q96KS0
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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