Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibody

Details for Product No. ABIN183112
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Antigen
Synonyms besc1, beta-ENaC, enacb, enacbeta, scneb, BESC1, ENaCb, ENaCbeta, SCNEB, BETA-ENAC, SCNN1B, RNENACB
Epitope
C-Term
(19), (19), (19), (19), (9), (6), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Rabbit, Dog (Canine), Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(83), (79), (62), (35), (34), (34), (34)
Host
Rabbit
(100), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (5), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(56), (38), (34), (21), (19), (17), (11), (11), (3), (3)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN183112
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human SCNN1B
Sequence QPDTAPRSPN TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI
Predicted Reactivity Bovine : 100 %, Goat : 100 %, Human : 100 %, Guinea pig : 90 %, Horse : 90 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SCNN1B
Background When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Molecular Weight 70 kDa
Gene ID 6338
NCBI Accession NP_000327, NM_000336
UniProt P51168
Research Area Cancer, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 640 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibody WB Suggested Anti-SCNN1B Antibody Titration: 0.125ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
anti-Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibody (2) WB Suggested Anti-SCNN1B
Antibody Titration: 0.125 µg/mL ELISA Titer: 1:.12500
Positive Control: Jurkat cell lysate
Background publications Snyder, Olson, Kabra et al.: "cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45753-8, 2004 (PubMed).

Validation Images
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