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Details for Product No. ABIN183112

Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B) (C-Term) antibody

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Antigen
Synonyms BESC1, ENaCb, ENaCbeta, SCNEB, RNENACB, BETA-ENAC, besc1, beta-ENaC, enacb, enacbeta, scneb, SCNN1B
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Rabbit, Dog (Canine), Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN183112
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-SCNN1B antibody: synthetic peptide directed towards the C terminal of human SCNN1B
Sequence QPDTAPRSPNTGPYPSEQALPIPGTPPPNYDSLRLQPLDV IESDSEGDAI
Predicted Reactivity Bovine : 100%, Goat : 100%, Human : 100%, Guinea pig : 92%, Horse : 92%, Mouse : 85%, Rat : 85%
Characteristics This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name SCNN1B
Background When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Molecular Weight 70kDa
Gene ID 6338
NCBI Accession NP_000327, NM_000336
UniProt P51168
Research Area Cancer, Metabolism
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-SCNN1B antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Snyder, Olson, Kabra et al.: "cAMP and serum and glucocorticoid-inducible kinase (SGK) regulate the epithelial Na(+) channel through convergent phosphorylation of Nedd4-2." in: The Journal of biological chemistry, Vol. 279, Issue 44, pp. 45753-8, 2004 (PubMed).

Alternatives for antigen "Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B)", type "Antibodies"
Hosts (71), (2), (1)
Reactivities (66), (64), (61), (34), (34), (34), (34)
Applications (45), (30), (27), (13), (12), (11), (3), (2), (2), (1)
Conjugates (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Epitopes (19), (18), (4), (3), (2), (2), (1), (1), (1), (1)
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