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CACNA2D1 antibody (Middle Region)

CACNA2D1 Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN183113
  • Target See all CACNA2D1 Antibodies
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    Binding Specificity
    • 12
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Rat, Mouse, Dog, Rabbit, Cow, Guinea Pig, Horse
    Host
    • 44
    • 1
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 21
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA2D1 antibody is un-conjugated
    Application
    • 29
    • 27
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PKSQEPVTLD FLDAELENDI KVEIRNKMID GESGEKTFRT LVKSQDERYI
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against CACNA2D1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CACNA2D1
    Top Product
    Discover our top product CACNA2D1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1091 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Tétreault, Bourdin, Briot, Segura, Lesage, Fiset, Parent: "Identification of Glycosylation Sites Essential for Surface Expression of the CaVα2δ1 Subunit and Modulation of the Cardiac CaV1.2 Channel Activity." in: The Journal of biological chemistry, Vol. 291, Issue 9, pp. 4826-43, (2016) (PubMed).

    Stotz, Barr, McRory, Chen, Jarvis, Zamponi: "Several structural domains contribute to the regulation of N-type calcium channel inactivation by the beta 3 subunit." in: The Journal of biological chemistry, Vol. 279, Issue 5, pp. 3793-800, (2004) (PubMed).

  • Target
    CACNA2D1 (Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 1 (CACNA2D1))
    Alternative Name
    CACNA2D1 (CACNA2D1 Products)
    Synonyms
    CACNA2D1 antibody, DKFZp469K2211 antibody, CACNA2 antibody, CACNL2A antibody, CCHL2A antibody, Ca(v)alpha2delta1 antibody, Cacna2 antibody, Cchl2a antibody, CCHLA2 antibody, DHSCCA antibody, calcium voltage-gated channel auxiliary subunit alpha2delta 1 antibody, calcium channel, voltage-dependent, alpha 2/delta subunit 1 antibody, calcium channel, voltage-dependent, alpha2/delta subunit 1 antibody, CACNA2D1 antibody, cacna2d1 antibody, Cacna2d1 antibody
    Background
    CACNA2D1 encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio.
    Alias Symbols: CACNA2, CCHL2A, CACNL2A
    Protein Interaction Partner: STT3B, RAB11A, NDUFS4, Cep76,
    Protein Size: 1091
    Molecular Weight
    120 kDa
    Gene ID
    781
    NCBI Accession
    NM_000722, NP_000713
    UniProt
    P54289
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