CLCN3 antibody (C-Term)

Catalog No. ABIN183185

Product Details anti-CLCN3 Antibody

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Binding Specificity: C-Term

Reactivity: Rat, Human, Mouse, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Horse, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCN3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VGDAFGREGI YEAHIRLNGY PFLDAKEEFT HTTLAADVMR PRRNDPPLAV L

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 91%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CLCN3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human CLCN3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 866 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CLCN3 antibody (ABIN183185)

Jensen, Nosjean, Dziegiel, Boutin, Sørensen, Karsdal, Henriksen: "A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).

Target Details for CLCN3

Target: CLCN3 (Chloride Channel 3 (CLCN3))

Alternative Name: CLCN3 (CLCN3 Products)

Synonyms: CLC3 antibody, ClC-3 antibody, Clc3 antibody, CLCN3 antibody, fb78c02 antibody, wu:fb78c02 antibody, clc3 antibody, clc-3 antibody, chloride voltage-gated channel 3 antibody, chloride channel, voltage-sensitive 3 antibody, chloride channel 3 antibody, chloride channel protein 3 antibody, chloride channel, voltage-sensitive 3 S homeolog antibody, CLCN3 antibody, Clcn3 antibody, clcn3 antibody, PTRG_03131 antibody, BDBG_05668 antibody, MCYG_04420 antibody, clcn3.S antibody

Background: CLCN3 plays an important role in the cell proliferation of vascular smooth muscle cells. The PDZ-binding isoform of CLCN3 resides in the Golgi where it co-localizes with a small amount of CFTR (cystic fibrosis transmembrane conductance regulator).
Alias Symbols: CLC3, ClC-3
Protein Interaction Partner: GOPC, SLC9A3R1, PDZK1, CLCN3, CFTR,
Protein Size: 866

Molecular Weight: 95 kDa

Gene ID: 1182

NCBI Accession: NM_173872, NP_776297

UniProt: P51790