GJB4 antibody (Middle Region)

Catalog No. ABIN183374

Product Details anti-GJB4 Antibody

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CPSLLVVMHV AYREERERKH HLKHGPNAPS LYDNLSKKRG GLWWTYLLSL

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against GJB4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJB4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 266 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJB4

Target: GJB4 (Gap Junction Protein, beta 4, 30.3kDa (GJB4))

Alternative Name: GJB4 (GJB4 Products)

Synonyms: GJB4 antibody, Cnx30.3 antibody, Cx30.3 antibody, Gjb-4 antibody, CX30.3 antibody, EKV antibody, gap junction protein beta 4 antibody, gap junction protein, beta 4 antibody, GJB4 antibody, Gjb4 antibody

Background: Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.
Alias Symbols: EKV, CX30.3
Protein Interaction Partner: UBC,
Protein Size: 266

Molecular Weight: 29 kDa

Gene ID: 127534

NCBI Accession: NM_153212, NP_694944

UniProt: Q9NTQ9