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ALX Homeobox 4 (ALX4) (C-Term) antibody

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Antigen
Synonyms im:7142878, zgc:162606, alx4, FND2, lst
Epitope
C-Term
(16), (15), (11), (6), (3), (2), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(52), (14), (8), (4), (3), (1)
Host
Rabbit
(41), (15)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(49), (24), (17), (4), (4), (3), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human ALX4
Blocking Peptide Blocking peptide for this product available: ABIN973160
Sequence SVSGAGSHVG QTHMGSLFGA ASLSPGLNGY ELNGEPDRKT SSIAALRMKA
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 90 %, Rat : 90 %
Characteristics This is a rabbit polyclonal antibody against ALX4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ALX4 (ALX4 Antibody Abstract)
Background Alx4 is a member of the family of transcription factors that contain the paired-type homeodomain. In contrast to other types of homeodomains, the paired-type homeodomain has been shown to mediate high-affinity sequence-specific DNA binding to palindromic elements as either homodimers or as heterodimers with other family members. Alx4 is co-expressed with Cart1 at several sites during development, including the craniofacial mesenchyme, the mesenchymal derivatives of neural crest cells in the first branchial arch and the limb bud mesenchyme.
Molecular Weight 44 kDa
Gene ID 60529
NCBI Accession NP_068745, NM_021926
UniProt Q9H161
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 411 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-ALX Homeobox 4 (ALX4) (C-Term) antibody (ABIN183395) WB Suggested Anti-ALX4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Mavrogiannis, Antonopoulou, Baxová et al.: "Haploinsufficiency of the human homeobox gene ALX4 causes skull ossification defects." in: Nature genetics, Vol. 27, Issue 1, pp. 17-8, 2001 (PubMed).

Catalog No. ABIN183395
$289.00
Plus shipping costs $45.00

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