CCL5 antibody (Middle Region)

Catalog No. ABIN183459

Product Details anti-CCL5 Antibody

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Dog, Rat, Guinea Pig, Cow, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YGSDTTPCCF AYLSLELPRA HVKEYFYTSS KCSNLAVVFV TRRNRQVCAN

Predicted Reactivity: Cow: 85%, Dog: 91%, Guinea Pig: 85%, Horse: 85%, Human: 85%, Mouse: 100%, Pig: 91%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CCL5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse CCL5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 91 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Alternative Name: CCL5 (CCL5 Products)

Synonyms: Rantes antibody, Scya5 antibody, D17S136E antibody, RANTES antibody, SCYA5 antibody, SIS-delta antibody, SISd antibody, TCP228 antibody, eoCP antibody, MuRantes antibody, C-C motif chemokine 5-like antibody, C-C motif chemokine ligand 5 antibody, chemokine (C-C motif) ligand 5 antibody, LOC100230935 antibody, CCL5 antibody, Ccl5 antibody

Background: Recently, it has been shown that genetic polymorphisms can result in diminished expression of CCL5, which results in increased susceptibility to and progression of infectious diseases. CCL5, together with Th cytokine mRNA expression, is temporally up-regulated during pneumococcal carriage. CCL5 is an essential factor for the induction and maintenance of protective pneumococcal immunity
Alias Symbols: SISd, Scya5, RANTES, TCP228, MuRante, MuRantes
Protein Interaction Partner: Ccr1,
Protein Size: 91

Molecular Weight: 10 kDa

Gene ID: 20304

NCBI Accession: NM_013653, NP_038681

UniProt: P30882

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration