anti-MEF2C antibody (Myocyte Enhancer Factor 2C) (N-Term)

Details for Product anti-MEF2C Antibody No. ABIN183480
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Antigen
Synonyms MEF2C, XMEF2C, si:ch211-202e12.2, C5DELq14.3, DEL5q14.3, 5430401D19Rik, 9930028G15Rik, AV011172, Mef2, RGD1563119, id:ibd5026, mef2c, wu:fc05b06, zgc:64184, zgc:85726
Epitope
N-Term
(41), (29), (26), (22), (21), (20), (17), (14), (13), (10), (6), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(316), (109), (73), (3), (2), (2), (1), (1), (1)
Host
Rabbit
(275), (39), (3)
Clonality
Polyclonal
Conjugate
This MEF2C antibody is un-conjugated
(19), (19), (19), (14), (14), (14), (5), (5), (5), (5), (5), (5), (5), (5)
Application
Western Blotting (WB)
(220), (135), (101), (67), (50), (39), (21), (19), (17), (9), (6), (5), (2), (1)
Pubmed 8 references available
Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of mouse MEF2C
Sequence SRTNSDIVEA LNKKENKGSE SPDPDSSYAL TPRTEEKYKK INEEFDNMIK
Predicted Reactivity Human : 100 %, Mouse : 100 %, Pig : 100 %
Characteristics This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name MEF2C (MEF2C Antibody Abstract)
Background MEF2C is a transcription regulator of slow fiber
Molecular Weight 48 kDa
Gene ID 17260
NCBI Accession NM_025282, NP_079558
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 432 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Myocyte Enhancer Factor 2C (MEF2C) (N-Term) antibody WB Suggested Anti-MEF2C Antibody Titration: 2.5ug/ml
ELISA Titer: 1:...
Product cited in: Law, Leung, Yau et al.: "Regulation of multiple transcription factors by reactive oxygen species and effects of pro-inflammatory cytokines released during myocardial infarction on cardiac differentiation of embryonic stem ..." in: International journal of cardiology, Vol. 168, Issue 4, pp. 3458-72, 2013 (PubMed).

Inagawa, Miyamoto, Yamakawa et al.: "Induction of cardiomyocyte-like cells in infarct hearts by gene transfer of Gata4, Mef2c, and Tbx5." in: Circulation research, Vol. 111, Issue 9, pp. 1147-56, 2012 (PubMed).

Escher, Schorderet, Cottet: "Altered expression of the transcription factor Mef2c during retinal degeneration in Rpe65-/- mice." in: Investigative ophthalmology & visual science, Vol. 52, Issue 8, pp. 5933-40, 2011 (PubMed).

Blin, Nury, Stefanovic et al.: "A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates." in: The Journal of clinical investigation, Vol. 120, Issue 4, pp. 1125-39, 2010 (PubMed).

Lombardi, Dong, Rodriguez et al.: "Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy." in: Circulation research, Vol. 104, Issue 9, pp. 1076-84, 2009 (PubMed).

Leschik, Stefanovic, Brinon et al.: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, 2008 (PubMed).

Background publications Shen, McElhinny, Cao et al.: "The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis." in: Genes & development, Vol. 20, Issue 6, pp. 675-88, 2006 (PubMed).

General Shen, Kamp, Gruendling et al.: "A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression." in: Genes & development, Vol. 20, Issue 23, pp. 3283-95, 2006 (PubMed).

Validation Images
Catalog No. ABIN183480
229.00 $
Plus shipping costs $45.00
Quantity
Price
100 μg
229.00 $

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