BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) antibody

Antigen: BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1)

Synonyms: BACH-1, BACH1, MGC112205, zgc:112205

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB)

Catalog no.: ABIN183588

Additional Information

Alternative name: BACH1

Gene ID: BACH1

UniProt: O14867

Immunogen: The immunogen for anti-BACH1 antibody: synthetic peptide directed towards the C terminal of human BACH1

Sequence: PPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGG ISDFCQQMTD

Cross-Reactivity: Human

Format: Lyophilized

Reconstitution: Add 100 µl of distilled water. Final anti-BACH1 antibody concentration is 1 mg/ml.

Description: BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.

Characteristics: Antigen Size: 736 amino acids

Molecular Weight: 82kDa

Application Details

Application Notes: WB Suggested Anti-BACH1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate.

Purification: Protein A purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-BACH1 Antibody Titration: 1.25ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate

Publications

Product: Litman, Peng, Jin et al.: "BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ." in: Cancer cell, Vol. 8, Issue 3, pp. 255-65, 2005 (PubMed).