LIM Homeobox Transcription Factor 1, beta (LMX1B) (C-Term) antibody

Details for Product No. ABIN183616
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Antigen
Synonyms LMX1.1, LMX1.2, LMX, LMX1, NPS1, lmx1b, lmx1b.1, Xlmx1b
Epitope
C-Term
(12), (8), (2), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Xenopus laevis, Human, Zebrafish (Danio rerio), Chicken
(51), (34), (20), (12), (12), (12)
Host
Rabbit
(43), (4), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (28), (10), (10), (5), (4), (1)
Pubmed 1 reference available
Quantity 100 µg
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Catalog No. ABIN183616
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human LMX1B
Sequence QSPYGSSDPF QQGLTPPQMP GNDSIFHDID SDTSLTSLSD CFLGSSDVGS
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %, African clawed frog : 90 %
Characteristics This is a rabbit polyclonal antibody against LMX1B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name LMX1B
Background LMX1B is essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Defects in LMX1B are the cause of nail-patella syndrome (NPS) also knowan as Onychoosteodysplasia.
Molecular Weight 42 kDa
Gene ID 4010
NCBI Accession NM_002316, NP_002307
UniProt Q6ISC9
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 372 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Bongers, Huysmans, Levtchenko et al.: "Genotype-phenotype studies in nail-patella syndrome show that LMX1B mutation location is involved in the risk of developing nephropathy." in: European journal of human genetics : EJHG, Vol. 13, Issue 8, pp. 935-46, 2005 (PubMed).

Validation Images
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