LMX1B antibody (C-Term)

Catalog No. ABIN183616

Product Details anti-LMX1B Antibody

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LMX1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QSPYGSSDPF QQGLTPPQMP GNDSIFHDID SDTSLTSLSD CFLGSSDVGS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against LMX1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human LMX1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LMX1B

Target: LMX1B (LIM Homeobox Transcription Factor 1, beta (LMX1B))

Alternative Name: LMX1B (LMX1B Products)

Synonyms: LMX1.2 antibody, NPS1 antibody, LMX antibody, LMX1 antibody, LMX1.1 antibody, lmx1b antibody, lmx1b.1 antibody, Xlmx1b antibody, lmx1b.2 antibody, LIM homeobox transcription factor 1 beta antibody, LIM homeobox transcription factor 1, beta b antibody, LIM homeobox transcription factor 1, beta, gene 1 S homeolog antibody, LIM homeobox transcription factor 1, beta a antibody, LMX1B antibody, Lmx1b antibody, lmx1bb antibody, lmx1b.1.S antibody, lmx1ba antibody

Background: LMX1B is essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels. Defects in LMX1B are the cause of nail-patella syndrome (NPS) also knowan as Onychoosteodysplasia.
Alias Symbols: NPS1, LMX1.2
Protein Interaction Partner: LDB1, APP, SSBP3, TCF3,
Protein Size: 372

Molecular Weight: 42 kDa

Gene ID: 4010

NCBI Accession: NM_002316, NP_002307

UniProt: Q6ISC9

Pathways: Dopaminergic Neurogenesis