KCNJ5 antibody (C-Term)

Catalog No. ABIN183662

Product Details anti-KCNJ5 Antibody

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RSRSPGSYKQ RETRKRAQRN PGEEQSRRND SRSHGTDLYR GEKMYREHPG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CIR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CIR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Alternative Name: CIR (KCNJ5 Products)

Synonyms: CIR antibody, GIRK4 antibody, KATP1 antibody, KIR3.4 antibody, LQT13 antibody, Kir3.4 antibody, GIRK-4 antibody, KATP-1 antibody, potassium voltage-gated channel subfamily J member 5 antibody, potassium inwardly-rectifying channel, subfamily J, member 5 antibody, KCNJ5 antibody, Kcnj5 antibody

Background: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 450

Molecular Weight: 52 kDa

Gene ID: 9541

NCBI Accession: NM_004882, NP_004873

UniProt: Q86X95

Pathways: Notch Signaling