You are viewing an incomplete version of our website. Please click to reload the website as full version.

SAP18 antibody (Sin3A-Associated Protein, 18kDa) (N-Term)

Details for Product anti-SAP18 Antibody No. ABIN183693, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms zgc:73118, C530046K05Rik, D11Ertd539e, EMegR4, Sinbp1, 2HOR0202, SAP18P
Alternatives
Epitope
N-Term
(16), (11), (7), (7), (4), (2), (2), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(41), (6), (6), (1)
Host
Rabbit
(34), (7)
Clonality
Polyclonal
Conjugate
This SAP18 antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(36), (22), (12), (7), (2), (1), (1), (1)
Pubmed 1 reference available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human SAP18
Blocking Peptide Blocking peptide for this product available: ABIN983387
Sequence EIKKEPEKPI DREKTCPLLL RVFTTNNGRH HRMDEFSRGN VPSSELQIYT
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against SAP18. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SAP18 (SAP18 Antibody Abstract)
Background Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.
Molecular Weight 18 kDa
Gene ID 10284
NCBI Accession NP_005861, NM_005870
UniProt O00422
Research Area Chromatin and Nuclear Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 153 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-SAP18 antibody (Sin3A-Associated Protein, 18kDa) (N-Term) (ABIN183693) anti-Sin3A-Associated Protein, 18kDa (SAP18) (N-Term) antibody
Background publications Zhang, Iratni, Erdjument-Bromage et al.: "Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex." in: Cell, Vol. 89, Issue 3, pp. 357-64, 1997 (PubMed).

Catalog No. ABIN183693
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)